Clever-1 (also known as Stabilin-1 and FEEL-1) is a scavenger receptor expressed on
lymphatic endothelial cells, sinusoidal endothelial cells and immunosuppressive monocytes …

Adeno-associated virus (AAV) vectors have gained tremendous attention as in vivo delivery
systems in gene therapy for inherited monogenetic diseases. First market approvals …

Oncolytic viruses have demonstrated selective replication and killing of tumor cells. Different
types of oncolytic viruses–adenoviruses, alphaviruses, herpes simplex viruses, Newcastle …

Neuroblastoma (NB) is a pediatric neuroendocrine neoplasm. It arises from the sympatho-
adrenal lineage of neural-crest-derived multipotent progenitor cells that fail to differentiate …

Existing marker-based methods of minimal residual disease (MRD) determination in
neuroblastoma do not effectively enrich for the circulating disease cell population. Given the …

Myeloid cells accumulate extensively in most tumors and play a critical role in
immunosuppression of the tumor microenvironment (TME). Like T cells, myeloid cells also …

It is well-known that the tumor microenvironment (TME) plays an important role in the
regulation of tumor growth and the efficacy of anti-tumor therapies. Recent studies have …

Simple Summary Incidence of thyroid cancer, including papillary thyroid cancer, is rapidly
increasing. Oncogenes, such as the BRAFV600E, have been identified, and their effect on …

Papillary thyroid carcinoma (PTC) is the most frequent histological subtype of thyroid
cancers (TC), and BRAFV600E genetic alteration is found in 60% of this endocrine cancer …