Objective: This study was a 20-year follow-up of offspring of depressed and nondepressed
parents to determine the magnitude and continuity of the risk of parental depression to the …

Objective: While the increased risk of psychopathology in the biological offspring of
depressed parents has been widely replicated, the long-term outcome through their full age …

Maternal depressive symptoms influence neurodevelopment in the offspring. Such effects
may appear to be gender-dependent. The present study examined contributions of prenatal …

ContextChildren of depressed parents have high rates of anxiety, disruptive, and depressive
disorders that begin early, often continue into adulthood, and are impairing. ObjectiveTo …

Background Antenatal maternal cortisol levels associate with alterations in the amygdala, a
structure associated with emotion regulation, in the offspring. However, because offspring …

Background Family and twin studies suggest that juvenile-onset major depressive disorder
(MDD) may be etiologically distinct from adult-onset MDD. This study is the first to distinguish …

Grounded in extensive research and clinical experience, this manual provides a complete
guide to interpersonal psychotherapy for depressed adolescents (IPT-A). IPT-A is an …

Background: We review the evidence for the familiality of major depressive disorder (MDD)
and the genetic aetiology of depressive symptoms in children and adolescents. Methods …

Background The familial nature of early-onset major depressive disorder (MDD) has been
documented in numerous family studies of adults and is supported by studies of offspring of …

We aim to provide a starting point toward the development of an evidence-based
assessment of depression in children and adolescents. We begin by discussing issues …