Tendon is an intricately organized connective tissue that efficiently transfers muscle force to
the bony skeleton. Its structure, function, and physiology reflect the extreme, repetitive …

In calcific tendinopathy (CT), calcium deposits in the substance of the tendon, with chronic
activity-related pain, tenderness, localized edema and various degrees of decreased range …

Stem cells have recently been isolated from humans and mice but not from rat tendon tissue.
This study reports the isolation and characterization of stem cells from rat tendon. Nucleated …

Collagen has a major role in the structural organization of tendons. Picrosirius red (PSR)
staining viewed under polarized light microscopy is the standard method to evaluate the …

The use of tendon-derived stem cells (TDSCs) as a cell source for musculoskeletal tissue
engineering has not been compared with that of bone marrow stromal cells (BMSC). This …

Pain and functional limitation are frequent in symptomatic tendinopathy. The essential lesion
of tendinopathy is a failed healing response. Understanding the cellular and molecular …

Chronic tendinopathy refers to a broad spectrum of pathological conditions in tendons and
their insertion, with symptoms including activity‐related chronic pain. To study the …

A greater understanding of the parturition process is essential in the prevention of preterm
birth, which occurs in 12.7% of infants born in the United States annually. Cervical …

Our understanding of the pathogenesis of" tendinopathy" is based on fragmented evidences
like pieces of a jigsaw puzzle. We propose a" failed healing theory" to knit these fragments …

Abnormal tendons are rarely ever repaired to the natural structure and morphology of
normal tendons. To better guide the repair and regeneration of injured tendons through a …