Burkitt lymphoma

C López, B Burkhardt, JKC Chan, L Leoncini… - Nature Reviews …, 2022 - nature.com
Burkitt lymphoma (BL) is an aggressive form of B cell lymphoma that can affect children and
adults. The study of BL led to the identification of the first recurrent chromosomal aberration …

Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment

Y Dai, C Xu, X Sun, X Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …

The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma

CB Steen, BA Luca, MS Esfahani, A Azizi, BJ Sworder… - Cancer cell, 2021 - cell.com
Biological heterogeneity in diffuse large B cell lymphoma (DLBCL) is partly driven by cell-of-
origin subtypes and associated genomic lesions, but also by diverse cell types and cell …

Genomic profiling for clinical decision making in lymphoid neoplasms

L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

[PDF][PDF] Tumor microenvironment: recent advances in various cancer treatments.

JJ Wang, KF Lei, F Han - European Review for Medical & …, 2018 - europeanreview.org
This is a review regarding different types of cancer treatments. We aimed at analyzing the
tumor microenvironment and the recent trends for the therapeutic applications and …

Follicular lymphoma

A Carbone, S Roulland, A Gloghini, A Younes… - Nature reviews Disease …, 2019 - nature.com
Follicular lymphoma (FL) is a systemic neoplasm of the lymphoid tissue displaying germinal
centre (GC) B cell differentiation. FL represents~ 5% of all haematological neoplasms and …

Adenosine-A2A receptor pathway in cancer immunotherapy

C Sun, B Wang, S Hao - Frontiers in immunology, 2022 - frontiersin.org
A2A receptors (A2AR), a typical GPCR with a high affinity for adenosine, was expressed in
many immune cells, such as regulatory T cells, cytotoxic T cells, macrophages, etc …

Principles in the design of ligand-targeted cancer therapeutics and imaging agents

M Srinivasarao, CV Galliford, PS Low - Nature reviews Drug discovery, 2015 - nature.com
Most cancer drugs are designed to interfere with one or more events in cell proliferation or
survival. As healthy cells may also need to proliferate and avoid apoptosis, anticancer …

Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL

F Vari, D Arpon, C Keane, MS Hertzberg… - Blood, The Journal …, 2018 - ashpublications.org
Much focus has been on the interaction of programmed cell death ligand 1 (PD-L1) on
malignant B cells with programmed cell death 1 (PD-1) on effector T cells in inhibiting …

Germinal centres and B cell lymphomagenesis

K Basso, R Dalla-Favera - Nature Reviews Immunology, 2015 - nature.com
Germinal centres (GCs) are involved in the selection of B cells secreting high-affinity
antibodies and are also the origin of most human B cell lymphomas. Recent progress has …