Equine infectious anemia and equine infectious anemia virus in 2013: a review

RF Cook, C Leroux, CJ Issel - Veterinary microbiology, 2013 - Elsevier
Equine infectious anemia and equine infectious anemia virus in 2013: A review -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

Molecular determinants that regulate plasma membrane association of HIV-1 Gag

V Chukkapalli, A Ono - Journal of molecular biology, 2011 - Elsevier
Human immunodeficiency virus type 1 assembly is a multistep process that occurs at the
plasma membrane (PM). Targeting and binding of Gag to the PM are the first steps in this …

Atomic view of the HIV-1 matrix lattice; implications on virus assembly and envelope incorporation

AB Samal, TJ Green, JS Saad - Proceedings of the …, 2022 - National Acad Sciences
During the late phase of HIV type 1 (HIV-1) infection cycle, the virally encoded Gag
polyproteins are targeted to the inner leaflet of the plasma membrane (PM) for assembly …

A plant virus hijacks phosphatidylinositol-3, 5-bisphosphate to escape autophagic degradation in its insect vector

H Wang, J Zhang, H Liu, M Wang, Y Dong, Y Zhou… - Autophagy, 2023 - Taylor & Francis
Hosts can initiate macroautophagy/autophagy as an antiviral defense response, while
viruses have developed multiple ways to evade the host autophagic degradation. However …

HIV type 1 Gag as a target for antiviral therapy

AA Waheed, EO Freed - AIDS research and human retroviruses, 2012 - liebertpub.com
The Gag proteins of HIV-1 are central players in virus particle assembly, release, and
maturation, and also function in the establishment of a productive infection. Despite their …

PI(4,5)P2 Clustering and Its Impact on Biological Functions

Y Wen, VM Vogt, GW Feigenson - Annual Review of …, 2021 - annualreviews.org
Located at the inner leaflet of the plasma membrane (PM), phosphatidyl-inositol 4, 5-
bisphosphate [PI (4, 5) P2] composes only 1–2 mol% of total PM lipids. With its synthesis …

Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers

J Vlach, JS Saad - Proceedings of the National Academy of …, 2013 - National Acad Sciences
Localization of the HIV type-1 (HIV-1) Gag protein on the plasma membrane (PM) for virus
assembly is mediated by specific interactions between the N-terminal myristoylated matrix …

Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636

D Sbrissa, OC Ikonomov, C Filios… - … of Physiology-Cell …, 2012 - journals.physiology.org
PIKfyve is an essential mammalian lipid kinase with pleiotropic cellular functions whose
genetic knockout in mice leads to preimplantation lethality. Despite several reports for …

The interplay between HIV-1 Gag binding to the plasma membrane and Env incorporation

RE Murphy, JS Saad - Viruses, 2020 - mdpi.com
Advancement in drug therapies and patient care have drastically improved the mortality
rates of HIV-1 infected individuals. Many of these therapies were developed or improved …

Gag localization and virus-like particle release mediated by the matrix domain of human T-lymphotropic virus type 1 Gag are less dependent on phosphatidylinositol …

J Inlora, V Chukkapalli, D Derse, A Ono - Journal of virology, 2011 - Am Soc Microbiol
The human immunodeficiency virus type 1 (HIV-1) Gag matrix (MA) domain facilitates Gag
targeting and binding to the plasma membrane (PM) during virus assembly. Interaction with …