The pathological processes leading to synapse loss, neuronal loss, brain atrophy and
gliosis in Alzheimer's disease (AD) and their relation to vascular disease and immunological …

Abstract Purpose of the Review Apolipoprotein (APO) A1, the main apolipoprotein of plasma
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …

The blood-brain barrier (BBB) is a dynamic but solid shield in the cerebral microvascular
system. It plays a pivotal role in maintaining central nervous system (CNS) homeostasis by …

Cholesterol homeostasis is a highly regulated process in human body because of its several
functions underlying the biology of cell membranes, the synthesis of all steroid hormones …

The vascular endothelium serves as a barrier between the intravascular and extravascular
compartments. High-density lipoproteins (HDL) have two kinds of interactions with this …

Several lines of epidemiological evidence link increased levels of high-density lipoprotein-
cholesterol (HDL-C) with lower risk of Alzheimer's disease (AD). This observed relationship …

We propose the hypothesis that small high‐density lipoprotein (HDL) particles reduce the
risk of Alzheimer's disease (AD) by virtue of their capacity to exchange lipids, affecting …

High-density lipoproteins (HDL) play a key role in cholesterol homeostasis maintenance in
the central nervous system (CNS), by carrying newly synthesized cholesterol from astrocytes …

The main role of cholesteryl ester transfer protein (CETP) is the transfer of cholesteryl esters
and triglycerides between high-density lipoprotein (HDL) particles and triglyceride-rich …

Alzheimer's disease (AD) represents a progressive amyloidogenic disorder whose
advancement is widely recognized to be connected to amyloid-β peptides and Tau …