Risk factors for eating disorders: findings from a rapid review
Background Risk factors represent a range of complex variables associated with the onset,
development, and course of eating disorders. Understanding these risk factors is vital for the …
development, and course of eating disorders. Understanding these risk factors is vital for the …
From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators
H Han, B Yi, R Zhong, M Wang, S Zhang, J Ma, Y Yin… - Microbiome, 2021 - Springer
Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …
[HTML][HTML] The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice
Y Fan, RK Støving, S Berreira Ibraim… - Nature …, 2023 - nature.com
Anorexia nervosa (AN) is an eating disorder with a high mortality. About 95% of cases are
women and it has a population prevalence of about 1%, but evidence-based treatment is …
women and it has a population prevalence of about 1%, but evidence-based treatment is …
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying
susceptibility genes could highlight the underlying pathophysiological mechanisms. We …
susceptibility genes could highlight the underlying pathophysiological mechanisms. We …
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
Genetic risk variants that have been identified in genome-wide association studies of
complex diseases are primarily non-coding. Translating these risk variants into mechanistic …
complex diseases are primarily non-coding. Translating these risk variants into mechanistic …
Could polygenic risk scores be useful in psychiatry?: a review
Importance Polygenic risk scores (PRS) are predictors of the genetic susceptibility to
diseases, calculated for individuals as weighted counts of thousands of risk variants in which …
diseases, calculated for individuals as weighted counts of thousands of risk variants in which …
The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study
Importance Most previous genome-wide association studies (GWAS) of depression have
used data from individuals of European descent. This limits the understanding of the …
used data from individuals of European descent. This limits the understanding of the …
Gut microbiota and psychiatric disorders: a two-sample Mendelian randomization study
JJ Ni, Q Xu, SS Yan, BX Han, H Zhang, XT Wei… - Frontiers in …, 2022 - frontiersin.org
Evidence supports the observational associations of gut microbiota with a variety of
psychiatric disorders, but the causal nature of such associations remains obscure. Aiming to …
psychiatric disorders, but the causal nature of such associations remains obscure. Aiming to …
Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders
Observational studies have reported the correlations between brain imaging-derived
phenotypes (IDPs) and psychiatric disorders; however, whether the relationships are causal …
phenotypes (IDPs) and psychiatric disorders; however, whether the relationships are causal …