Macromolecular information transfer

S Samokhvalova, JF Lutz - Angewandte Chemie, 2023 - Wiley Online Library
Macromolecular information transfer can be defined as the process by which a coded
monomer sequence is communicated from one macromolecule to another. In such a transfer …

Synthetically encoded complementary oligomers

RK Weigel, A Rangamani, CA Alabi - Nature Reviews Chemistry, 2023 - nature.com
Creating the next generation of advanced materials will require controlling molecular
architecture to a degree typically achieved only in biopolymers. Sequence-defined polymers …

Length and Sequence-Selective Polymer Synthesis Templated by a Combination of Covalent and Noncovalent Base-Pairing Interactions

F Balduzzi, V Munasinghe, ON Evans… - Journal of the …, 2024 - ACS Publications
Information can be encoded and stored in sequences of monomer units organized in linear
synthetic polymers. Replication of sequence information is of fundamental importance in …

Covalent Template-Directed Synthesis: A Powerful Tool for the Construction of Complex Molecules

P Bolgar, M Dhiman, D Núñez-Villanueva… - Chemical …, 2024 - ACS Publications
Template-directed synthesis has become a powerful methodology to access complex
molecules. Noncovalent templating has been widely used in the last few decades, but less …

100th anniversary of macromolecular science viewpoint: Toward artificial life-supporting macromolecules

JF Lutz - ACS Macro Letters, 2020 - ACS Publications
Terrestrial Life is based on polymers. In all known living organisms, DNA stores genetic
information, mutates, self-replicates, and guides the synthesis of messenger molecules …

Folding and duplex formation in sequence-defined aniline benzaldehyde oligoarylacetylenes

KR Strom, JW Szostak - Journal of the American Chemical Society, 2022 - ACS Publications
In all known genetic polymers, molecular recognition via hydrogen bonding between
complementary subunits underpins their ability to encode and transmit information, to form …

Stimuli‐Responsive Molecular Duplexes Displaying Duplex‐to‐Duplex Switching

S Lee, G Song, KS Jeong - Angewandte Chemie International …, 2024 - Wiley Online Library
Synthetic duplexes with high stabilities have promising potential for mimicking biomolecular
functions and developing supramolecular smart materials. Herein, we describe the synthesis …

H-bond templated oligomer synthesis using a covalent primer

D Núñez-Villanueva, CA Hunter - Journal of the American …, 2022 - ACS Publications
Template-directed synthesis of nucleic acids in the polymerase chain reaction is based on
the use of a primer, which is elongated in the replication process. The attachment of a high …

Sequence-selective dynamic covalent assembly of information-bearing oligomers

SC Leguizamon, TF Scott - Nature Communications, 2020 - nature.com
Relatively robust dynamic covalent interactions have been employed extensively to mediate
molecular self-assembly reactions; however, these assembly processes often do not …

Sequence information transfer using covalent template-directed synthesis

D Núñez-Villanueva, M Ciaccia, G Iadevaia… - Chemical …, 2019 - pubs.rsc.org
Template-directed synthesis is the biological method for the assembly of oligomers of
defined sequence, providing the molecular basis for replication and the process of evolution …