Covering: 2000 to 2019 According to a 2012 survey from the Centers for Disease Control
and Prevention, approximately 18% of the US population uses natural products (including …

Malaria, in particular infection with P. falciparum (the most lethal of the human malaria
parasite species, responsible for nearly one million deaths every year), is one of the most …

In 2010 there were more than 200 million cases of malaria, and at least 655,000 deaths. The
World Health Organization has recommended artemisinin-based combination therapies …

The therapeutic areas of infectious diseases and oncology have benefited from abundant
scaffold diversity in natural products, able to interact with many specific targets within the cell …

Plants of Artemisia annua produce artemisinin, a sesquiterpene lactone widely used in
malaria treatment. Amorpha-4, 11-diene synthase (ADS), a sesquiterpene synthase, and …

Covering: 2005 to 2007 Natural product and natural product-derived compounds that are
being evaluated in clinical trials or are in registration (as at 31st December 2007) have been …

Terpenes are naturally occurring substances produced by a wide variety of plants and
animals. A broad range of the biological properties of terpenoids is described, including …

Improvement of quality of life and survival of cancer patients will be greatly enhanced by the
development of highly effective drugs to selectively kill malignant cells. Artemisinin and its …

Terpenoids represent a diverse class of molecules that provide a wealth of opportunities to
address many human health and societal issues. The expansive array of structures and …

The Chinese medicinal plant Artemisia annua L.(Qinghao) is the only known source of the
sesquiterpene artemisinin (Qinghaosu), which is used in the treatment of malaria …