Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …

Since the first two complete bacterial genome sequences were published in 1995, the
science of bacteria has dramatically changed. Using third-generation DNA sequencing, it is …

Antimicrobial resistance (AMR) is one of the most important health threats globally. The
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …

Objectives WGS-based antimicrobial susceptibility testing (AST) is as reliable as phenotypic
AST for several antimicrobial/bacterial species combinations. However, routine use of WGS …

Background As the cost of sequencing has declined, clinical diagnostics based on next
generation sequencing (NGS) have become reality. Diagnostics based on sequencing will …

For nearly 100 years serotyping has been the gold standard for the identification of
Salmonella serovars. Despite the increasing adoption of DNA-based subtyping approaches …

Although the impact of host genetics on gut microbial diversity and the abundance of specific
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …

Abstract In South Africa, a progressive increase in listeriosis cases was noted from mid-June
2017, heralding what was to become the world's largest listeriosis outbreak. A total of 1060 …

Multi-country outbreaks of foodborne bacterial disease present challenges in their detection,
tracking, and notification. As food is increasingly distributed across borders, such outbreaks …

Salmonella Infantis is one of the five serovars most frequently causing human salmonellosis
in Europe, mainly associated with poultry. A clone harbouring a conjugative plasmid of …