Abnormal production of inflammatory mediators is believed to play an important role in the
pathogenesis of psoriasis. Emerging data, both in mice and in humans, put the spotlight on a …

Psoriasis is one of the most common immune-mediated chronic, inflammatory skin diseases
characterized by hyperproliferative keratinocytes and infiltration of T cells, dendritic cells …

Psoriasis is a common T-cell-mediated skin disease with 2–3% prevalence worldwide.
Psoriasis is considered to be an autoimmune disease, but the precise nature of the …

Although anti-tumor necrosis factor (TNF) agents are highly effective in the treatment of
psoriasis, 2–5% of treated patients develop psoriasis-like skin lesions called paradoxical …

Psoriasis is a common and chronic inflammatory skin disease in which T cells play a key
role. Effective treatment heals the skin without scarring, but typically psoriasis recurs in …

A key challenge in psoriasis therapy is the tendency for lesions to recur in previously
affected anatomical locations after treatment discontinuation following lesion resolution …

Chronic and excessive inflammation in skin and joints causes significant morbidity in
psoriasis patients. As a prevalent T lymphocyte–mediated disorder, psoriasis, as well as the …

Psoriasis is a common autoimmune skin disease characterized by T cell-mediated
hyperproliferation of keratinocytes. The disease has a strong but complex genetic …

Psoriasis is a chronic inflammatory disorder of the skin that is mediated by T cells, dendritic
cells and inflammatory cytokines. We now understand many of the cellular alterations that …

BACKGROUND: Psoriasis appears to have increased cardiovascular morbidity. The
underlying pathogenetic mechanisms remain unclear. Multiple factors, including systemic …