The fat mass and obesity-associated (FTO) gene was the first obesity-susceptibility gene
identified through a genome-wide association study (GWAS). A growing number of studies …

Epigenetic and epitranscriptomic modifications that regulate physiological processes of an
organism at the DNA and RNA levels, respectively, are novel therapeutic candidates for …

Neuronal death following ischemia is the primary cause of death and disability in patients
with ischemic stroke. N6-methyladenosine (m6A) modification plays essential role in various …

We previously showed that knockdown or deletion of Fos downstream transcript (FosDT; a
stroke-induced brain-specific long noncoding RNA) is neuroprotective. We presently tested …

Post‐stroke neuroinflammation is pivotal in brain repair, yet persistent inflammation can
aggravate ischemic brain damage and hamper recovery. Following stroke, specific …

Background Traumatic brain injury (TBI) is a common complication of acute and severe
neurosurgery. Remodeling of N6-methyladenosine (m6A) stabilization may be an attractive …

Abstract The microRNA-21 (miR-21) levels in the brain are crucial in determining post-stroke
brain damage and recovery. The miR-21 exerts neuroprotection by targeting mRNAs that …

The role of m6A modification in the regulation of the immune microenvironment (IME) of
ischemic stroke (IS) is barely known. Thus, we aim to investigate the impact of m6A …

This study aimed to explore whether USP18 regulates cerebral ischemia–reperfusion (I/R)
injury via fat mass and obesity-associated proteins (FTO)-mediated NCOA4. Middle cerebral …

We previously showed that stroke alters circular RNA (circRNA) expression profiles. Many
circRNAs undergo epitranscriptomic modifications, particularly methylation of adenosine to …