Multidrug resistance (MDR) is a major obstacle in the therapy of infectious diseases and
cancer. One of the major mechanisms of MDR is the overexpression of efflux pumps (EPs) …

Cancer is recognized as the major cause of death worldwide and the most challenging
public health issues. Tumor cells exhibit molecular adaptations and metabolic reprograming …

Background Colorectal cancer (CRC) is a highly prevalent cancer type with limited targeted
therapies available and 5-year survival rate, particularly for late-stage patients. There have …

Colorectal cancer (CRC) is one of the leading causes of death, accounting for more than half
a million deaths annually. Even worse, an increasing number of cancer cases are …

Over the past few decades, the life expectancy of humankind has increased significantly due
to advancements in life sciences and medical research, particularly given our increasing …

Cancer accounts for 10 million deaths in 2022, especially lung and colorectal cancers.
Although there have been numerous remedies for advanced-stage cancer including …

Fenotiazyny są lekami neuroleptycznymi, które w połowie XX w. wywołały rewolucję w
psychiatrii. Choć od tego czasu minęło wiele lat, związki te ciągle pozostają w kręgu …

Phenothiazines are antipsychotic drugs used in the treatment of psychosis, including
schizophrenia. Until the discovery of the phenothiazine derivative chlorpromazine at the …