The role of plant‐associated rhizobacteria in plant growth, biocontrol and abiotic stress management

BA Bhat, L Tariq, S Nissar, ST Islam… - Journal of Applied …, 2022 - academic.oup.com
The rhizosphere is the region around the plant roots where maximum microbial activities
occur. In the rhizosphere, microorganisms' beneficial and harmful activities affect plant …

Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic tools …

SP Gaudêncio, E Bayram, L Lukić Bilela, M Cueto… - Marine drugs, 2023 - mdpi.com
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

COCONUT online: collection of open natural products database

M Sorokina, P Merseburger, K Rajan, MA Yirik… - Journal of …, 2021 - Springer
Natural products (NPs) are small molecules produced by living organisms with potential
applications in pharmacology and other industries as many of them are bioactive. This …

Chemical language models enable navigation in sparsely populated chemical space

MA Skinnider, RG Stacey, DS Wishart… - Nature Machine …, 2021 - nature.com
Deep generative models are powerful tools for the exploration of chemical space, enabling
the on-demand generation of molecules with desired physical, chemical or biological …

Artificial intelligence in microbial natural product drug discovery: current and emerging role

VJ Sahayasheela, MB Lankadasari, VM Dan… - Natural product …, 2022 - pubs.rsc.org
Covering: up to the end of 2022 Microorganisms are exceptional sources of a wide array of
unique natural products and play a significant role in drug discovery. During the golden era …

The essentials of marine biotechnology

A Rotter, M Barbier, F Bertoni, AM Bones… - Frontiers In marine …, 2021 - frontiersin.org
Coastal countries have traditionally relied on the existing marine resources (eg, fishing,
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …

NPASS database update 2023: quantitative natural product activity and species source database for biomedical research

H Zhao, Y Yang, S Wang, X Yang, K Zhou… - Nucleic Acids …, 2023 - academic.oup.com
Quantitative activity and species source data of natural products (NPs) are important for drug
discovery, medicinal plant research, and microbial investigations. Activity values of NPs …

Applications of virtual screening in bioprospecting: facts, shifts, and perspectives to explore the chemo-structural diversity of natural products

K Santana, LD Do Nascimento, A Lima e Lima… - Frontiers in …, 2021 - frontiersin.org
Natural products are continually explored in the development of new bioactive compounds
with industrial applications, attracting the attention of scientific research efforts due to their …

The year 2020 in natural product bioinformatics: an overview of the latest tools and databases

MH Medema - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2020 Bioinformatic approaches to document and analyse chemical structures,
biosynthetic gene clusters and analytical data play an important role in the study of natural …

Investigation of the molecular landscape of bacterial aromatic polyketides by global analysis of type II polyketide synthases

S Chen, C Zhang, L Zhang - Angewandte Chemie, 2022 - Wiley Online Library
Aromatic polyketides biosynthesized by microorganisms are a prominent class of natural
products widely used in clinical treatments. Although genome mining approaches have …