Novel methodologies for chemical activation in organic synthesis under solvent-free reaction conditions

CG Avila-Ortiz, E Juaristi - Molecules, 2020 - mdpi.com
One central challenge for XXI century chemists is the development of sustainable processes
that do not represent a risk either to humanity or to the environment. In this regard, the …

1, 3‐Dipolar Cycloaddition Reactions of Nitrile Oxides under “Non‐Conventional” Conditions: Green Solvents, Irradiation, and Continuous Flow

J Plumet - ChemPlusChem, 2020 - Wiley Online Library
Abstract The 1, 3‐dipolar cycloaddition reactions (DCs) of nitrile oxides (NOs) to alkenes
and alkynes are useful methods for the synthesis of 2‐isoxazolines and isoxazoles …

Carboxymethyl chitosan-glycerol multi-aldehyde based self-healing hydrogel system

C Bayram - International Journal of Biological Macromolecules, 2023 - Elsevier
The superiority of self-healing hydrogel systems with dynamic covalent chemistry is the
ability to establish the gel network structure despite changes in ambient conditions such as …

The application of anisole in greener solid-phase peptide synthesis protocols–Compatibility with green bases in Fmoc removal and new green binary mixture for …

A Přibylka, M Pastorek, M Grepl, EP Schütznerová - Tetrahedron, 2021 - Elsevier
As a step toward green Fmoc solid-phase peptide synthesis (SPPS), we explored the
compatibility of the green bases morpholine, 1, 8-diazabicyclo [5.4. 0] undec-7-ene (DBU) …

A greener approach for the synthesis of pyrido[2,3‐d]pyrimidine derivatives in glycerol under microwave heating

LA Martinho, CKZ Andrade - Journal of Heterocyclic Chemistry, 2022 - Wiley Online Library
Herein, we report the multicomponent synthesis of pyrido [2, 3‐d] pyrimidine derivatives from
6‐aminouracil, aromatic aldehydes, and malononitrile in glycerol as a green solvent under …

Microwave-assisted protocol for green functionalization of thiophenes with a Pd/β-cyclodextrin cross-linked nanocatalyst

S Tabasso, E Calcio Gaudino, E Acciardo… - Frontiers in …, 2020 - frontiersin.org
Microwaves (MW) are often the most efficient, in terms of heat exchange and conversion
rate, of all the energy sources used to promote chemical reactions thanks to fast volumetric …

[HTML][HTML] One-Pot, Multi-Component Green Microwave-Assisted Synthesis of Bridgehead Bicyclo [4.4. 0] boron Heterocycles and DNA Affinity Studies

P Paisidis, MG Kokotou, A Kotali, G Psomas… - International Journal of …, 2024 - mdpi.com
Anthranilic acids, salicylaldehydes and arylboronic acids reacted in EtOH/H2O (1/3) at 150°
C under microwave irradiation for 1 h to give, in excellent yields and purity, twenty-three …

Microwave-Assisted Synthesis of Biologically Relevant Six-Membered N-Heterocycles

M Kamboj, S Bajpai, G Pandey… - Current Microwave …, 2023 - ingentaconnect.com
One of the most efficient non-conventional heating methods is microwave irradiation. In
organic synthesis, microwave irradiation has become a popular heating technique as it …

Broadening the reaction scope of unprotected aldoses via their corresponding nitrones: 1, 3-dipolar cycloadditions with alkenes

G Messire, F Massicot, L Pascual, E Riguet… - Organic & …, 2020 - pubs.rsc.org
Condensation reactions of unprotected tetroses and pentoses with hydroxylamines afforded
nitrones, which were easily converted to densely functionalized isoxazolidines in the …

Microwave-assisted synthesis of hydroxamic acid incorporated quinazolin-4 [3H]-one derivatives

C Mikra, Z Melissari, MG Kokotou, P Gritzapis… - Sustainable Chemistry …, 2022 - Elsevier
Abstract A series of 3-hydroxy, 3-ethoxy and 3-benzyloxy-2-methylquinazolin-4 [3H]-one
derivatives were synthesized in one-pot four-component or in a two-step protocol under …