Keeping mRNPs in check during assembly and nuclear export

E Tutucci, F Stutz - Nature reviews Molecular cell biology, 2011 - nature.com
The cell nucleus is an intricate organelle that coordinates multiple activities that are
associated with DNA replication and gene expression. In all eukaryotes, it stores the genetic …

[HTML][HTML] Phase separation of intrinsically disordered nucleolar proteins relate to localization and function

F Guillen-Chable, A Bayona… - International Journal of …, 2021 - mdpi.com
The process of phase separation allows for the establishment and formation of
subcompartmentalized structures, thus enabling cells to perform simultaneous processes …

[HTML][HTML] The human CCHC-type zinc finger nucleic acid-binding protein binds G-rich elements in target mRNA coding sequences and promotes translation

D Benhalevy, SK Gupta, CH Danan, S Ghosal, HW Sun… - Cell reports, 2017 - cell.com
The CCHC-type zinc finger nucleic acid-binding protein (CNBP/ZNF9) is conserved in
eukaryotes and is essential for embryonic development in mammals. It has been implicated …

[HTML][HTML] Genomic insights into the host specific adaptation of the Pneumocystis genus

OH Cissé, L Ma, JP Dekker, PP Khil, JH Youn… - Communications …, 2021 - nature.com
Pneumocystis jirovecii, the fungal agent of human Pneumocystis pneumonia, is closely
related to macaque Pneumocystis. Little is known about other Pneumocystis species in …

Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human

F Birzele, T Fauti, H Stahl, MC Lenter… - Nucleic acids …, 2011 - academic.oup.com
Regulatory T-cells (Treg) play an essential role in the negative regulation of immune
answers by developing an attenuated cytokine response that allows suppressing …

Yeast screen for modifiers of C9orf72 poly(glycine-arginine) dipeptide repeat toxicity

N Chai, AD Gitler - FEMS Yeast Research, 2018 - academic.oup.com
A hexanucleotide repeat expansion in the C9orf72 gene has been identified as the most
common cause of amyotrophic lateral sclerosis and frontotemporal dementia. The expanded …

[HTML][HTML] Analysis and prediction of the critical regions of antimicrobial peptides based on conditional random fields

KY Chang, T Lin, LY Shih, CK Wang - PloS one, 2015 - journals.plos.org
Antimicrobial peptides (AMPs) are potent drug candidates against microbes such as
bacteria, fungi, parasites, and viruses. The size of AMPs ranges from less than ten to …

Protein arginine methylation in Saccharomyces cerevisiae

JKK Low, MR Wilkins - The FEBS journal, 2012 - Wiley Online Library
Recent research has implicated arginine methylation as a major regulator of cellular
processes, including transcription, translation, nucleocytoplasmic transport, signalling, DNA …

[HTML][HTML] The glycine-rich domain of GRP7 plays a crucial role in binding long RNAs and facilitating phase separation

KL Lühmann, S Seemann, N Martinek, S Ostendorp… - Scientific Reports, 2024 - nature.com
Microscale thermophoresis (MST) is a well-established method to quantify protein-RNA
interactions. In this study, we employed MST to analyze the RNA binding properties of …

[HTML][HTML] Fibrillarin ribonuclease activity is dependent on the GAR domain and modulated by phospholipids

F Guillen-Chable, U Rodriguez Corona… - Cells, 2020 - mdpi.com
Fibrillarin is a highly conserved nucleolar methyltransferase responsible for ribosomal RNA
methylation across evolution from Archaea to humans. It has been reported that fibrillarin is …