Bile acids are increasingly appearing in the spotlight owing to their novel impacts on various
host processes. Similarly, there is growing attention on members of the microbiota that are …

Bile acids are steroids generated at the interface of host and intestinal microbiota. While
primary bile acids are generated in the liver from cholesterol metabolism, secondary bile …

Abstract microbeMASST, a taxonomically informed mass spectrometry (MS) search tool,
tackles limited microbial metabolite annotation in untargeted metabolomics experiments …

Bacteria in the gastrointestinal tract produce amino acid bile acid amidates that can affect
host-mediated metabolic processes,,,,–; however, the bacterial gene (s) responsible for their …

Bile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-
soluble vitamins while shaping the gut microbiome because of their antimicrobial …

The field of bile acid microbiology in the gastrointestinal tract is going through a current
rebirth after a peak of activity in the late 1970s and early 1980s. This renewed activity is a …

Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …

Commensal microorganisms in the human gut produce numerous metabolites by using
small molecules derived from the host or diet as precursors. Host or dietary lipid molecules …

Around two-thirds of chronic human disease can not be explained by genetics alone. The
Lancet Commission on Pollution and Health estimates that 16% of global premature deaths …

Human physiology is profoundly influenced by the gut microbiota, which generates a wide
array of metabolites. These microbiota-derived compounds serve as signaling molecules …