The CD19 antigen plays an important role in clinical oncology. In normal cells, it is the most
ubiquitously expressed protein in the B lymphocyte lineage. CD19 expression is induced at …

VER A DECADE HAS passed since ''Immunologic Classification of Leukemia and
Lymphoma''by Foon and Todd was published in Blood. 1 Over this decade, flow Acute …

The bcl-2 gene becomes transcriptionally deregulated in the majority of low-grade non-
Hodgkin lymphomas as a result of t (14; 18) translocations that place the bcl-2 gene at …

Purpose: To determine, in a randomized clinical trial, whether high-dose therapy (HDT)
followed by autologous stem-cell transplantation is more effective than standard treatment …

Metastatic relapse in patients with solid tumors is caused by systemic preoperative or
perioperative dissemination of tumor cells. The presence of individual tumor cells in bone …

Successive oncogenic steps are necessary to generate cancer. In many B-cell lymphomas,
chromosomal translocations are considered to be an early oncogenic hit. We investigated …

In this article, we report on 904 patients undergoing transplantation for follicular lymphoma.
A total of 176 (19%) received allogeneic, 131 (14%) received purged autologous, and 597 …

As the above-mentioned cellular and molecular parameters and newly identified biologic
features are evaluated in larger numbers of patients with aggressive NHL, the biologic …

The disorders classified as non-Hodgkin's lymphoma are increasing in frequency in the
United States, with more than 35,000 cases diagnosed annually. In recent years, there have …

Conventional chemotherapy has failed to substantially prolong survival for patients with
advanced follicular lymphoma. To improve outcomes, the German Low-Grade Lymphoma …