[HTML][HTML] Metabolomics-guided utilization of beneficial microbes for climate-resilient crops

OS Olanrewaju, BR Glick, OO Babalola - Current Opinion in Chemical …, 2024 - Elsevier
In the rhizosphere, plants and microbes communicate chemically, especially under
environmental stress. Over millions of years, plants and their microbiome have coevolved …

A marine-derived fatty acid targets the cell membrane of Gram-positive bacteria

I Upender, O Yoshida, A Schrecengost… - Journal of …, 2023 - Am Soc Microbiol
The rapid evolution of antibiotic resistance is shrinking our stockpile of commercially
available antibiotics. Therefore, new antimicrobials with novel mechanisms of action (MoAs) …

Diversity, composition and potential roles of sedimentary microbial communities in different coastal substrates around subtropical Okinawa Island, Japan

K Hamamoto, M Mizuyama, M Nishijima… - Environmental …, 2024 - Springer
Background Marine benthic prokaryotic communities play crucial roles in material recycling
within coastal environments, including coral reefs. Coastal sedimentary microbiomes are …

Small molecule in situ resin capture provides a compound first approach to natural product discovery

A Bogdanov, MN Salib, AB Chase… - Nature …, 2024 - nature.com
Culture-based microbial natural product discovery strategies fail to realize the extraordinary
biosynthetic potential detected across earth's microbiomes. Here we introduce Small …

The Natural Products Discovery Center: Release of the first 8490 sequenced strains for exploring Actinobacteria biosynthetic diversity

E Kalkreuter, SA Kautsar, D Yang, CD Bader… - …, 2024 - pmc.ncbi.nlm.nih.gov
Actinobacteria, the bacterial phylum most renowned for natural product discovery, has been
established as a valuable source for drug discovery and biotechnology but is …

Comparative genomics reveals insight into the phylogeny and habitat adaptation of novel Amycolatopsis species, an endophytic actinomycete associated with scab …

T Wannawong, W Mhuantong, P Macharoen… - Frontiers in Plant …, 2024 - frontiersin.org
A novel endophytic actinomycete, strain MEP2-6T, was isolated from scab tissues of potato
tubers collected from Mae Fag Mai Sub-district, San Sai District, Chiang Mai Province …

Unlocking the biosynthetic potential and taxonomy of the Antarctic microbiome along temporal and spatial gradients

W Medeiros, K Hidalgo, T Leão… - Microbiology …, 2024 - Am Soc Microbiol
Extreme environments, such as Antarctica, select microbial communities that display a range
of evolutionary strategies to survive and thrive under harsh environmental conditions. These …

Biosynthetic gene clusters from uncultivated soil bacteria of the Atacama Desert

CM Andreani-Gerard, V Cambiazo, M González - Msphere, 2024 - journals.asm.org
Soil microorganisms mediate several biological processes through the secretion of natural
products synthesized in specialized metabolic pathways, yet functional characterization in …

Bacterial diversity and chemical ecology of natural product–producing bacteria from Great Salt Lake sediment

ER Bring Horvath, WJ Brazelton, MC Kim… - ISME …, 2024 - academic.oup.com
Abstract Great Salt Lake (GSL), located northwest of Salt Lake City, UT, is the largest
terminal lake in the USA. While the average salinity of seawater is~ 3.3%, the salinity in GSL …

Succession of microbial community composition and secondary metabolism during marine biofilm development

PK Bech, SA Jarmusch, JA Rasmussen… - ISME …, 2024 - academic.oup.com
In nature, secondary metabolites mediate interactions between microorganisms residing in
complex microbial communities. However, the degree to which community dynamics can be …