Metabolic engineering advances and prospects for amino acid production

VF Wendisch - Metabolic engineering, 2020 - Elsevier
Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …

[HTML][HTML] Bacteria as an alternate biofactory for carotenoid production: A review of its applications, opportunities and challenges

S Ram, M Mitra, F Shah, SR Tirkey, S Mishra - Journal of Functional Foods, 2020 - Elsevier
Carotenoid has gained a reputation amongst researchers for its robust antioxidant
capabilities. This review reasons the inevitability of carotenoid for a larger role than just …

Targeting pathway expression to subcellular organelles improves astaxanthin synthesis in Yarrowia lipolytica

Y Ma, J Li, S Huang, G Stephanopoulos - Metabolic Engineering, 2021 - Elsevier
Metabolic engineering approaches for the production of high-value chemicals in
microorganisms mostly use the cytosol as general reaction vessel. However, sequestration …

Metabolically engineered Corynebacterium glutamicum for bio-based production of chemicals, fuels, materials, and healthcare products

J Becker, CM Rohles, C Wittmann - Metabolic engineering, 2018 - Elsevier
Corynebacterium glutamicum is a major workhorse in industrial biotechnology. For the past
several decades, this soil bacterium has been used to produce the amino acids l-glutamate …

Carotenoids and their health benefits as derived via their interactions with gut microbiota

A Eroglu, IS Al'Abri, RE Kopec, N Crook, T Bohn - Advances in Nutrition, 2023 - Elsevier
Carotenoids have been related to a number of health benefits. Their dietary intake and
circulating levels have been associated with a reduced incidence of obesity, diabetes …

Bacterial pigments: sustainable compounds with market potential for pharma and food industry

CK Venil, L Dufossé, P Renuka Devi - Frontiers in Sustainable Food …, 2020 - frontiersin.org
The continued universal application of synthetic colorants for decades have caused
environmental pollutions and human health vulnerabilities. So, it was indispensable to …

Microbial chassis development for natural product biosynthesis

X Xu, Y Liu, G Du, R Ledesma-Amaro, L Liu - Trends in biotechnology, 2020 - cell.com
Engineering microbial cells to efficiently synthesize high-value-added natural products has
received increasing attention in recent years. In this review, we describe the pipeline to build …

[HTML][HTML] Modular engineering for microbial production of carotenoids

C Li, CA Swofford, AJ Sinskey - Metabolic Engineering Communications, 2020 - Elsevier
There is an increasing demand for carotenoids due to their applications in the food, flavor,
pharmaceutical and feed industries, however, the extraction and synthesis of these …

Bacterial pigments and their multifaceted roles in contemporary biotechnology and pharmacological applications

H Agarwal, S Bajpai, A Mishra, I Kohli, A Varma… - Microorganisms, 2023 - mdpi.com
Synthetic dyes and colourants have been the mainstay of the pigment industry for decades.
Researchers are eager to find a more environment friendly and non-toxic substitute because …

Reprogramming microorganisms for the biosynthesis of astaxanthin via metabolic engineering

X Wan, XR Zhou, G Moncalian, L Su, WC Chen… - Progress in Lipid …, 2021 - Elsevier
There is an increasing demand for astaxanthin in food, feed, cosmetics and pharmaceutical
applications because of its superior anti-oxidative and coloring properties. However …