[HTML][HTML] Drug-induced oxidative stress in cancer treatments: Angel or devil?

H Jiang, J Zuo, B Li, R Chen, K Luo, X Xiang, S Lu… - Redox Biology, 2023 - Elsevier
Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …

Role of endoplasmic reticulum stress in drug‐induced toxicity

F Foufelle, B Fromenty - Pharmacology research & …, 2016 - Wiley Online Library
Drug‐induced toxicity is a key issue for public health because some side effects can be
severe and life‐threatening. These adverse effects can also be a major concern for the …

Reactive oxygen and nitrogen species in carcinogenesis: implications of oxidative stress on the progression and development of several cancer types

J Kruk, HY Aboul-Enein - Mini reviews in medicinal chemistry, 2017 - ingentaconnect.com
Background: The body of evidence available from published literature during the past three
decades indicates that reactive oxygen species and reactive nitrogen species can induce …

Arsenic: a review of the element's toxicity, plant interactions, and potential methods of remediation

BE Hettick, JE Canas-Carrell, AD French… - Journal of agricultural …, 2015 - ACS Publications
Arsenic is a naturally occurring element with a long history of toxicity. Sites of contamination
are found worldwide as a result of both natural processes and anthropogenic activities. The …

Arsenic or/and antimony induced mitophagy and apoptosis associated with metabolic abnormalities and oxidative stress in the liver of mice

G Zhong, F Wan, S Wu, X Jiang, Z Tang… - Science of the Total …, 2021 - Elsevier
Arsenic and antimony are coexisting cumulative environmental pollutants that cause severe
and extensive biological toxicity. However, their interactions and toxic mechanisms in the …

Dual effect of oxidative stress on leukemia cancer induction and treatment

UK Udensi, PB Tchounwou - Journal of Experimental & Clinical Cancer …, 2014 - Springer
Oxidative stress (OS) has been characterized by an imbalance between the production of
reactive oxygen species (ROS) and a biological system's ability to repair oxidative damage …

State of the science review of the health effects of inorganic arsenic: perspectives for future research

PB Tchounwou, CG Yedjou, UK Udensi… - Environmental …, 2019 - Wiley Online Library
Human exposure to inorganic arsenic (iAs) is a global health issue. Although there is strong
evidence for iAs‐induced toxicity at higher levels of exposure, many epidemiological studies …

Cadmium chloride induces DNA damage and apoptosis of human liver carcinoma cells via oxidative stress

A Skipper, JN Sims, CG Yedjou… - International journal of …, 2016 - mdpi.com
Cadmium is a heavy metal that has been shown to cause its toxicity in humans and animals.
Many documented studies have shown that cadmium produces various genotoxic effects …

Current status and future prospects of nanomedicine for arsenic trioxide delivery to solid tumors

M Sönksen, K Kerl, H Bunzen - Medicinal Research Reviews, 2022 - Wiley Online Library
Despite having a rich history as a poison, arsenic and its compounds have also gained a
great reputation as promising anticancer drugs. As a pioneer, arsenic trioxide has been …

Natural agents targeting mitochondria in cancer

S Mani, G Swargiary, KK Singh - International journal of molecular …, 2020 - mdpi.com
Mitochondria are the key energy provider to highly proliferating cancer cells, and are
subsequently considered one of the critical targets in cancer therapeutics. Several …