Synaptopathies are a class of neurodevelopmental disorders caused by modification in
genes coding for synaptic proteins. These proteins oversee the process of …

Synaptic transmission is the communication between a presynaptic and a postsynaptic
neuron, and the subsequent processing of the signal. These processes are complex and …

Synapsins (Syns) are phosphoproteins strongly involved in neuronal development and
neurotransmitter release. Three distinct genes SYN1, SYN2 and SYN3, with elevated …

Dietary restriction, such as low glycemic index diet (LGID), have been successfully used to
treat drug-resistant epilepsy. However, if such diet could also counteract antiepileptogenesis …

Synapsins are a family of neuronal phosphoproteins associated with the cytosolic surface of
synaptic vesicles. Experimental evidence suggests a role for synapsins in synaptic vesicle …

Synapsins are pre-synaptic vesicle-associated proteins linked to the pathogenesis of
epilepsy through genetic association studies in humans. Deletion of synapsins causes an …

The highly homologous nerve terminal phosphoproteins synapsin I and synapsin II have
been linked to the pathogenesis of epilepsy through associations between synapsin gene …

Neuronal circuit disturbances that lead to hyperexcitability in the cortico-hippocampal
network are one of the landmarks of temporal lobe epilepsy. The dentate gyrus (DG) network …

Neurotransmitters can be released either synchronously or asynchronously with respect to
action potential timing. Synapsins (Syns) are a family of synaptic vesicle (SV) …

The synapsin family offers a strong linkage between synaptic mechanisms and the epileptic
phenotype. Synapsins are phosphoproteins reversibly associated with synaptic vesicles …