Neural circuit motifs in valence processing

KM Tye - Neuron, 2018 - cell.com
How do our brains determine whether something is good or bad? How is this computational
goal implemented in biological systems? Given the critical importance of valence processing …

Neurotensin orchestrates valence assignment in the amygdala

H Li, P Namburi, JM Olson, M Borio, ME Lemieux… - Nature, 2022 - nature.com
The ability to associate temporally segregated information and assign positive or negative
valence to environmental cues is paramount for survival. Studies have shown that different …

Neurotensin in reward processes

ML Torruella-Suárez, ZA McElligott - Neuropharmacology, 2020 - Elsevier
Neurotensin (NTS) is a neuropeptide neurotransmitter expressed in the central and
peripheral nervous systems. Many studies over the years have revealed a number of roles …

A deficit of brain dystrophin impairs specific amygdala GABAergic transmission and enhances defensive behaviour in mice

M Sekiguchi, K Zushida, M Yoshida, M Maekawa… - Brain, 2009 - academic.oup.com
Duchenne muscular dystrophy (DMD) is accompanied by cognitive deficits and psychiatric
symptoms. In the brain, dystrophin, the protein responsible for DMD, is localized to a subset …

Substance P and neurotensin in the limbic system: Their roles in reinforcement and memory consolidation

L Lénárd, K László, E Kertes, T Ollmann… - Neuroscience & …, 2018 - Elsevier
Substance P (SP) and neurotensin (NT) are neuropeptides isolated in the periphery and in
the central nervous system. They are involved in various regulatory processes in the …

Diverse actions of the modulatory peptide neurotensin on central synaptic transmission

CW Tschumi, MJ Beckstead - European Journal of …, 2019 - Wiley Online Library
Neurotensin (NT) is a 13 amino acid neuropeptide that is expressed throughout the central
nervous system and is implicated in the etiology of multiple diseases and disorders. Many …

Loss of TET activity in the postnatal mouse brain perturbs synaptic gene expression and impairs cognitive function

JW Liu, ZQ Zhang, ZC Zhu, K Li, Q Xu, J Zhang… - Neuroscience …, 2024 - Springer
Abstract Conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) by ten-
eleven translocation (TET) family proteins leads to the accumulation of 5hmC in the central …

Activation of dopaminergic D2/D3 receptors modulates dorsoventral connectivity in the hippocampus and reverses the impairment of working memory after nerve …

H Cardoso-Cruz, M Dourado, C Monteiro… - Journal of …, 2014 - Soc Neuroscience
Dopamine plays an important role in several forms of synaptic plasticity in the hippocampus,
a crucial brain structure for working memory (WM) functioning. In this study, we evaluated …

Anticonvulsant neuropeptides as drug leads for neurological diseases

CR Robertson, SP Flynn, HS White, G Bulaj - Natural Product Reports, 2011 - pubs.rsc.org
Covering: 1995 to 2010 Anticonvulsant neuropeptides are best known for their ability to
suppress seizures and modulate pain pathways. Galanin, neuropeptide Y, somatostatin …

Development-dependent behavioral change toward pups and synaptic transmission in the rhomboid nucleus of the bed nucleus of the stria terminalis

T Amano, S Shindo, C Yoshihara, Y Tsuneoka… - Behavioural Brain …, 2017 - Elsevier
Sexually naïve male C57BL/6 mice aggressively bite unfamiliar pups. This behavior, called
infanticide, is considered an adaptive reproductive strategy of males of polygamous species …