The cerebellar cortex

C Hull, WG Regehr - Annual review of neuroscience, 2022 - annualreviews.org
The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …

Neocortex–cerebellum circuits for cognitive processing

MJ Wagner, L Luo - Trends in neurosciences, 2020 - cell.com
Although classically thought of as a motor circuit, the cerebellum is now understood to
contribute to a wide variety of cognitive functions through its dense interconnections with the …

Shared cortex-cerebellum dynamics in the execution and learning of a motor task

MJ Wagner, TH Kim, J Kadmon, ND Nguyen, S Ganguli… - Cell, 2019 - cell.com
Throughout mammalian neocortex, layer 5 pyramidal (L5) cells project via the pons to a vast
number of cerebellar granule cells (GrCs), forming a fundamental pathway. Yet, it is …

Genetic effects on cerebellar structure across mouse models of autism using a magnetic resonance imaging atlas

PE Steadman, J Ellegood, KU Szulc… - Autism …, 2014 - Wiley Online Library
Magnetic resonance imaging (MRI) of autism populations is confounded by the inherent
heterogeneity in the individuals' genetics and environment, two factors difficult to control for …

Synaptic mechanisms for associative learning in the cerebellar nuclei

R Broersen, C Albergaria, D Carulli, MR Carey… - Nature …, 2023 - nature.com
Associative learning during delay eyeblink conditioning (EBC) depends on an intact
cerebellum. However, the relative contribution of changes in the cerebellar nuclei to learning …

Interactions between purkinje cells and granule cells coordinate the development of functional cerebellar circuits

ME van der Heijden, RV Sillitoe - Neuroscience, 2021 - Elsevier
Cerebellar development has a remarkably protracted morphogenetic timeline that is
coordinated by multiple cell types. Here, we discuss the intriguing cellular consequences of …

Towards higher sensitivity and stability of axon diameter estimation with diffusion‐weighted MRI

F Sepehrband, DC Alexander… - NMR in …, 2016 - Wiley Online Library
Diffusion‐weighted MRI is an important tool for in vivo and non‐invasive axon morphometry.
The ActiveAx technique utilises an optimised acquisition protocol to infer orientationally …

Cerebellar zonal patterning relies on Purkinje cell neurotransmission

JJ White, M Arancillo, TL Stay… - Journal of …, 2014 - Soc Neuroscience
Cerebellar circuits are patterned into an array of topographic parasagittal domains called
zones. The proper connectivity of zones is critical for motor coordination and motor learning …

Oscillating gradient diffusion MRI reveals unique microstructural information in normal and hypoxia‐ischemia injured mouse brains

D Wu, LJ Martin, FJ Northington… - Magnetic resonance in …, 2014 - Wiley Online Library
Purpose We investigated whether oscillating gradient diffusion MRI (dMRI) can provide
information on brain microstructural changes after formaldehyde fixation and after hypoxic …

Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies

V Refolo, F Bez, A Polissidis, D Kuzdas-Wood… - Acta neuropathologica …, 2018 - Springer
Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder
characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α …