Invasive candidiasis

C Lass-Flörl, SS Kanj, NP Govender… - Nature Reviews …, 2024 - nature.com
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …

Critical appraisal beyond clinical guidelines for intraabdominal candidiasis

E Maseda, I Martín-Loeches, R Zaragoza, J Pemán… - Critical Care, 2023 - Springer
Background Regardless of the available antifungals, intraabdominal candidiasis (IAC)
mortality continues to be high and represents a challenge for clinicians. Main body This …

Invasive fungal diseases in adult patients in intensive care unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and …

M Bassetti, DR Giacobbe, C Agvald-Ohman… - Intensive Care …, 2024 - Springer
Purpose The aim of this document was to develop standardized research definitions of
invasive fungal diseases (IFD) in non-neutropenic, adult patients without classical host …

Intra-abdominal infection and sepsis in immunocompromised intensive care unit patients: Disease expression, microbial aetiology, and clinical outcomes

JA Paiva, J Rello, C Eckmann, M Antonelli… - European Journal of …, 2024 - Elsevier
We compared epidemiology of intra-abdominal infection (IAI) between immunocompromised
and non-immunocompromised ICU patients and identified risk factors for mortality. We …

Blood and intra-abdominal Candida spp. from a multicentre study conducted in Madrid using EUCAST: emergence of fluconazole resistance in Candida parapsilosis, low …

J Díaz-García, A Gómez, M Machado… - Journal of …, 2022 - academic.oup.com
Objectives We prospectively monitored the epidemiology and antifungal susceptibility of
Candida spp. from blood cultures and intra-abdominal samples in patients admitted to …

Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis

E Novy, C Roger, JA Roberts, MO Cotta - Critical Care, 2023 - Springer
Intra-abdominal candidiasis (IAC) is one of the most common of invasive candidiasis
observed in critically ill patients. It is associated with high mortality, with up to 50% of deaths …

Optimized Treatment of Nosocomial Peritonitis

JJ De Waele, F Coccolini, L Lagunes, E Maseda… - Antibiotics, 2023 - mdpi.com
This comprehensive review aims to provide a practical guide for intensivists, focusing on
enhancing patient care associated with nosocomial peritonitis (NP). It explores the …

SARS-CoV-2 vaccination in solid-organ transplant recipients

M Peghin, E Graziano, PA Grossi - Vaccines, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has posed significant global
challenges for solid organ transplant (SOT) recipients. Mortality rates of COVID-19 in this …

Combination of serum and peritoneal 1.3-beta-d-glucan can rule out intra-abdominal candidiasis in surgical critically ill patients: a multicenter prospective study

E Novy, J Rivière, M Nguyen, G Arfeuille, G Louis… - Critical Care, 2023 - Springer
Background Intra-abdominal candidiasis (IAC) is difficult to predict in critically ill patients with
intra-abdominal infection, leading to the overuse of antifungal treatments. Serum and …

[HTML][HTML] Antifungal resistance in Candida spp within the intra-abdominal cavity: study of resistance acquisition in patients with serial isolates

J Díaz-García, M Machado, L Alcalá, E Reigadas… - Clinical Microbiology …, 2023 - Elsevier
Objectives Antifungal susceptibility testing is mostly conducted on blood-cultured Candida
spp isolates. Because the intra-abdominal cavity has been highlighted as a hidden …