The focus of perioperative pain management should be to attempt to minimise the
nociceptive input and reduce the risk of transition to central sensitisation. Gabapentinoids …

Introduction Ocular barriers hinder drug delivery and reduce drug bioavailability. This article
focuses on enhancing drug absorption across the corneal and conjunctival epithelium. Both …

Most dry eye syndromes (DES) are caused by oxidative stress and an overactive
inflammatory response, leading to tear deficiency and excessive tear evaporation …

Dry eye disease (DED) is a high prevalent multifactorial disease characterized by a lack of
homeostasis of the tear film which causes ocular surface inflammation, soreness, and visual …

Neuropathic pain in humans results from an injury or disease of the somatosensory nervous
system at the peripheral or central level. Despite the considerable progress in pain …

Ocular inflammation is one of the most common comorbidities associated to ophthalmic
surgeries and disorders. Since conventional topical ophthalmic treatments present …

The valorization of food wastes is a challenging opportunity for a green, sustainable, and
competitive development of industry. Approximately 30 million m3 of olive mill wastewater …

Intervertebral disc degeneration (IDD) and associated conditions are an important problem
in modern medicine. The onset of IDD may be in childhood and adolescence in patients with …

Mangosteen fruit has been used for various disorders, including pain. The effects of alpha‐
mangostin, the main component of mangosteen, on the neuropathic pain caused by chronic …

Introduction This study aimed to prepare cholesterol and stearic acid-based solid lipid
nanoparticles of gabapentin (GAB-SLNs) for protection against streptozotocin (STZ)-induced …