Synthesis and diverse biological activities of substituted indole β-carbolines: a review

SZ Zulkifli, NH Pungot, AS Saaidin, NA Jani… - Natural Product …, 2024 - Taylor & Francis
Abstract β-Carboline bearing indole is one of the heterocyclic compounds that play a vital
role in medicinal chemistry with various pharmacological effects such as anticancer, anti …

Design, synthesis, antitumor, and antiplasmodial evaluation of new 7-chloroquinoline–benzimidazole hybrids

L Krstulović, V Rastija, L Pessanha de Carvalho, J Held… - Molecules, 2024 - mdpi.com
Newly synthesized 7-chloro-4-aminoquinoline–benzimidazole hybrids were characterized
by NMR and elemental analysis. Compounds were tested for their effects on the growth of …

In silico Approaches for Exploring the Pharmacological Activities of Benzimidazole Derivatives: A Comprehensive Review

M Srivastava, K Singh, S Kumar… - Mini Reviews in …, 2024 - ingentaconnect.com
Background: This article reviews computational research on benzimidazole derivatives.
Cytotoxicity for all compounds against cancer cell lines was measured and the results …

Design and synthesis of large Stokes shift DNA dyes with reduced genotoxicity

X Rao, K Zhou, J Tu, Y Lei, Q Li, X Hong… - Biochemical and …, 2024 - Elsevier
Despite intensive search over the past decades, only a few small-molecule DNA fluorescent
dyes were found with large Stokes shifts. These molecules, however, are often too toxic for …

Kajian Farmakoinformatika Senyawa Caulerchlorin dan Racemosin sebagai kandidat Antimalaria

DRT Sari, N Humairoh, IQ Lailaty… - … : The Journal of …, 2024 - jurnalsaintek.uinsa.ac.id
Caulerchlorin and racemosin were bioactive compounds containing in Caulerpa racemosa
macroalgae. Previous study, those compounds promoted therapeutical target on metabolic …

Review of synthesis process of nitrobenzimidazole derivatives

A El Alami, A El Maraghi, F Youssoufi… - Synthetic …, 2024 - Taylor & Francis
Nitrobenzimidazoles have become increasingly important in recent years, particularly in the
design of new classes of compounds with demonstrated activity in medicinal, therapeutic …

Modeling of Benzimidazole Derivatives as Antimalarial Agents using QSAR Analysis

R Hadanu, M Sitorus - Makara Journal of Science, 2024 - scholarhub.ui.ac.id
In this study, quantitative structure–activity relationship (QSAR) analysis was conducted on
20 homologous compounds of benzimidazole derivatives. The structures of the …

Synthesis, Characterization, Biological Activity, and Molecular Docking Study of Some New Sulfamethoxazole Derivatives.

AG Sager, JK Abaies, RA Issa - Baghdad Science Journal, 2024 - bsj.uobaghdad.edu.iq
In this paper, new Sulfamethoxazole derivatives were studied in order to improve the
treatment efficiency of this medicinal compound. Six compounds of Schiff bases were …

Efecto de la rigidez eritrocitaria como biomarcador en la invasión de Plasmodium falciparum

ED Alaín Borbón - 2024 - up-rid.up.ac.pa
La malaria es una enfermedad transmitida por parásitos del género Plasmodium que se
trasmite por la picadura de mosquitos hembras del género Anopheles que inoculan el …

[PDF][PDF] Recent Bioactive Benzimidazole Derivatives: A Review

A Rathod - 2023 - researchgate.net
Benzimidazoles (BZ) are medicinally significant scaffolds due its pharmaceutical potential as
an antitumor, antagonist, antidiabetic, anti-Neuroprotective, antiulcer etc. Now Days …