Leukemia is a malignancy initiated by uncontrolled proliferation of hematopoietic stem cell
from the B and T lineages, resulting in destruction of hematopoietic system. The …

Tuberculosis is the leading cause of death globally that is due to a single pathogen, and up
to a fifth of patients with tuberculosis in high-incidence countries are children younger than …

Purpose Non-invasive imaging is a key clinical tool for detection and treatment monitoring of
infections. Existing clinical imaging techniques are frequently unable to distinguish infection …

Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of
immunocompromised humans, caused by the opportunistic fungal pathogen Aspergillus …

Tools for noninvasive detection of bacterial pathogens are needed but are not currently
available for clinical use. We have previously shown that para-aminobenzoic acid (PABA) …

Fluorescence-guided surgery (FGS) is an evolving field that seeks to identify important
anatomic structures or physiologic phenomena with helpful relevance to the execution of …

Despite the introduction of many novel diagnostic techniques and newer treatment agents,
tuberculosis (TB) remains a major cause of death from an infectious disease worldwide. With …

Ebola virus (EBOV) disease is characterized by lymphopenia, breach in vascular integrity,
cytokine storm, and multiorgan failure. The pathophysiology of organ involvement, however …

Since most d-amino acids (DAAs) are utilized by bacterial cells but not by mammalian
eukaryotic hosts, recently DAA-based molecular imaging strategies have been extensively …

Positron emission tomography combined with computed tomography (PET/CT) is a nuclear
imaging technique which is increasingly being used in infectious diseases. Because …