Microglia are innate immune cells of the central nervous system that sense extracellular
cues. Brain injuries, inflammation, and pathology evoke dynamic structural responses in …

Based on electrophysiological, neurochemical and neuropharmacological approaches, it is
currently accepted that serotonin (5-HT) and dopamine (DA) function to promote waking (W) …

Objective The authors conducted a 15-week randomized controlled trial of the alpha-1
adrenoreceptor antagonist prazosin for combat trauma nightmares, sleep quality, global …

BACKGROUND: Excessive brain responsiveness to norepinephrine appears to contribute to
post-traumatic stress disorder (PTSD), particularly at night. Prazosin, a brain active alpha-1 …

Our knowledge of the form of lateralized sleep behavior, known as unihemispheric slow
wave sleep (USWS), seen in all members of the order Cetacea examined to date, is …

Nightmares and disruptive nocturnal behaviors that develop after traumatic experiences
have long been recognized as having different clinical characteristics that overlap with other …

Abstract Study Objectives: This study compared the effects of atomoxetine and
methylphenidate on the sleep of children with attention-deficit/hyperactivity disorder (ADHD) …

Sleep disorders have emerged as highly prevalent conditions in the last 50–75 y. Along with
improved understanding of such disorders, the realization that perturbations in sleep …

BackgroundPrazosin has been an accepted treatment for patients with post-traumatic stress
disorder (PTSD) who experience sleep disturbances, including nightmares. Results of a …

Diabetes increases the likelihood of developing depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …