Embracing diversity in the 5-HT neuronal system

BW Okaty, KG Commons, SM Dymecki - Nature Reviews Neuroscience, 2019 - nature.com
Neurons that synthesize and release 5-hydroxytryptamine (5-HT; serotonin) express a core
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …

The placenta‐brain‐axis

CS Rosenfeld - Journal of neuroscience research, 2021 - Wiley Online Library
All mammalian species depend on the placenta, a transient organ, for exchange of gases,
nutrients, and waste between the mother and conceptus. Besides serving as a conduit for …

The politics of life itself

N Rose - Theory, culture & society, 2001 - journals.sagepub.com
This article explores contemporary biopolitics in the light of Michel Foucault's oft quoted
suggestion that contemporary politics callslife itself'into question. It suggests that recent …

Dorsal raphe neurons signal reward through 5-HT and glutamate

Z Liu, J Zhou, Y Li, F Hu, Y Lu, M Ma, Q Feng, J Zhang… - Neuron, 2014 - cell.com
The dorsal raphe nucleus (DRN) in the midbrain is a key center for serotonin (5-
hydroxytryptamine; 5-HT)-expressing neurons. Serotonergic neurons in the DRN have been …

A transient placental source of serotonin for the fetal forebrain

A Bonnin, N Goeden, K Chen, ML Wilson, J King… - Nature, 2011 - nature.com
Abstract Serotonin (5-hydroxytryptamine or 5-HT) is thought to regulate neurodevelopmental
processes through maternal–fetal interactions that have long-term mental health …

Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation

S Brummelte, E Mc Glanaghy, A Bonnin, TF Oberlander - Neuroscience, 2017 - Elsevier
Abstract The neurotransmitter serotonin (5-HT) plays a central role in brain development,
regulation of mood, stress reactivity and risk of psychiatric disorders, and thus alterations in …

The developmental role of serotonin: news from mouse molecular genetics

P Gaspar, O Cases, L Maroteaux - Nature Reviews Neuroscience, 2003 - nature.com
New genetic models that target the serotonin system show that transient alterations in
serotonin homeostasis cause permanent changes to adult behaviour and modify the fine …

Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre-and post-synaptic 5-HT1A receptor expression

PR Albert, F Vahid-Ansari, C Luckhart - Frontiers in behavioral …, 2014 - frontiersin.org
Decreased serotonergic activity has been implicated in anxiety and major depression, and
antidepressants directly or indirectly increase the long-term activity of the serotonin system …

The ascent of mouse: advances in modelling human depression and anxiety

JF Cryan, A Holmes - Nature reviews Drug discovery, 2005 - nature.com
Psychiatry has proven to be among the least penetrable clinical disciplines for the
development of satisfactory in vivo model systems for evaluating novel treatment …

Conditional anterograde tracing reveals distinct targeting of individual serotonin cell groups (B5–B9) to the forebrain and brainstem

A Muzerelle, S Scotto-Lomassese, JF Bernard… - Brain Structure and …, 2016 - Springer
Serotoninergic innervation of the central nervous system is provided by hindbrain raphe
nuclei (B1–B9). The extent to which each raphe subdivision has distinct topographic …