Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications

L Dayon, O Cominetti, M Affolter - Expert review of proteomics, 2022 - Taylor & Francis
Introduction Biological fluids are routine samples for diagnostic testing and monitoring.
Blood samples are typically measured because of their moderate invasive collection and …

High-throughput proteomics and AI for cancer biomarker discovery

Q Xiao, F Zhang, L Xu, L Yue, OL Kon, Y Zhu… - Advanced drug delivery …, 2021 - Elsevier
Biomarkers are assayed to assess biological and pathological status. Recent advances in
high-throughput proteomic technology provide opportunities for developing next generation …

HBFP: a new repository for human body fluid proteome

D Shao, L Huang, Y Wang, X Cui, Y Li, Y Wang… - Database, 2021 - academic.oup.com
Body fluid proteome has been intensively studied as a primary source for disease biomarker
discovery. Using advanced proteomics technologies, early research success has resulted in …

Human body-fluid proteome: quantitative profiling and computational prediction

L Huang, D Shao, Y Wang, X Cui, Y Li… - Briefings in …, 2021 - academic.oup.com
Empowered by the advancement of high-throughput bio technologies, recent research on
body-fluid proteomes has led to the discoveries of numerous novel disease biomarkers and …

[HTML][HTML] Urinary complement proteins and risk of end-stage renal disease: quantitative urinary proteomics in patients with type 2 diabetes and biopsy-proven diabetic …

L Zhao, Y Zhang, F Liu, H Yang, Y Zhong… - Journal of …, 2021 - Springer
Purpose To investigate the association between urinary complement proteins and renal
outcome in biopsy-proven diabetic nephropathy (DN). Methods Untargeted proteomic and …

Spatial proteome profiling by immunohistochemistry-based laser capture microdissection and data-independent acquisition proteomics

P Huang, Q Kong, W Gao, B Chu, H Li, Y Mao… - Analytica Chimica …, 2020 - Elsevier
Understanding the tumor heterogeneity through spatially resolved proteome profiling is
important for biomedical research and clinical application. Laser capture microdissection …

[HTML][HTML] Identification of pathogens from native urine samples by MALDI-TOF/TOF tandem mass spectrometry

D Oros, M Ceprnja, J Zucko, M Cindric, A Hozic… - Clinical proteomics, 2020 - Springer
Background Reliable high-throughput microbial pathogen identification in human urine
samples is crucial for patients with cystitis symptoms. Currently employed methods are time …

Advancing serum peptidomic profiling by data-independent acquisition for clear-cell renal cell carcinoma detection and biomarker discovery

L Lin, J Zheng, F Zheng, Z Cai, Q Yu - Journal of proteomics, 2020 - Elsevier
The analysis of serum endogenous peptides holds promise for disease study and drug
discovery, whereas it is relatively unexplored given its challenges in analysis reproducibility …

[HTML][HTML] Proteomic approaches for characterizing renal cell carcinoma

DJ Clark, H Zhang - Clinical Proteomics, 2020 - Springer
Renal cell carcinoma is among the top 15 most commonly diagnosed cancers worldwide,
comprising multiple sub-histologies with distinct genomic, proteomic, and clinicopathological …