Memory consumption of de Bruijn graphs is often prohibitive. Most de Bruijn graph-based
assemblers reduce the complexity by compacting paths into single vertices, but this is …

Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …

Micro-organisms play key roles in various ecosystems, but many of their functions and
interactions remain undefined. To investigate the ecological relevance of microbial …

Today most population genomic studies of nonmodel organisms either sequence a subset of
the genome deeply in each individual or sequence pools of unlabelled individuals. With a …

Among the most common forms of interaction between species are those between hosts and
their parasites and they have important implications for evolutionary theory. Understanding …

Background Data volumes generated by next-generation sequencing (NGS) technologies is
now a major concern for both data storage and transmission. This triggered the need for …

Abstract SNPs (Single Nucleotide Polymorphisms) are genetic markers whose precise
identification is a prerequisite for association studies. Methods to identify them are currently …

In vitro and in vivo evolution experiments on Escherichia coli revealed several principles of
bacterial adaptation. However, few data are available in the literature describing the …

Key message NGS-assisted super pooling emerging as powerful tool to accelerate gene
mapping and haplotype association analysis within target region uncovering specific linkage …

Background Progress in genetics and breeding in pea still suffers from the limited availability
of molecular resources. SNP markers that can be identified through affordable sequencing …