Despite being largely preventable through early vaccination and screening strategies,
cervical cancer is the most common type of gynecological malignancy worldwide and …

Suicide gene therapy involves introducing viral or bacterial genes into tumor cells, which
enables the conversion of a nontoxic prodrug into a toxic‐lethal drug. The application of the …

The combination of the choline binding domain of the amidase N-acetylmuramoyl-L-alanine
(CLytA)-D-amino acid oxidase (DAAO)(CLytA-DAAO) and D-Alanine induces cell death in …

In this study, various N-heterocyclic nitro prodrugs (NHN1-16) containing pyrimidine, triazine
and piperazine rings were designed and synthesized. The final compounds were identified …

Nanotechnology is having a great deal of public interest, due to its wide array of applications
in biomedical research including drug delivery, biosensors, imaging, stem cells …

Oral cancers (OCs), being one of the frequent malignancies in the head and neck region,
need prompt diagnosis and treatment. Apart from basic therapeutic modalities …

In this study, a series of trinitroaniline derivatives (TNA1‐8) were synthesized and
investigated as potential antitumor agents for enzyme‐prodrug therapy. Enzymatic efficiency …