Free fatty acids (FFAs) play numerous vital roles in the organism, such as contribution to
energy generation and reserve, serving as an essential component of the cell membrane, or …

Insulin is a critical hormone that promotes energy storage in various tissues, as well as
anabolic functions. Insulin resistance significantly reduces these responses, resulting in …

Background. The primary malignant brain tumor glioblastoma multiforme (GBM) is most
commonly detected in individuals over 60 years old. The standard therapeutic approach for …

Extensive research has been carried out to understand and elucidate the mechanisms of
paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular …

High-density lipoproteins (HDL) are well known for their protective role against the
development and progression of atherosclerosis. Atheroprotection is mainly due to the key …

Idiopathic inflammatory myopathy (commonly known as myositis) is a group of immune-
related diseases characterized by muscle damage, weakness, and fatigue with unknown …

Lipotoxicity is defined as a prolonged metabolic imbalance of lipids that results in ectopic fat
distribution in peripheral organs such as the liver, heart, and kidney. The harmful …

Astragalus membranaceus (AM), used in traditional Chinese medicine, has been shown to
enhance immune functions, and recently, its anti‐inflammatory effects were identified …

In this study, we aimed to determine whether liraglutide could effectively reduce insulin
resistance (IR) by regulating Sestrin2 (SESN2) expression in L6 rat skeletal muscle cells by …

Accumulation of excess saturated free fatty acids such as palmitate (PAL) in skeletal muscle
leads to reductions in mitochondrial integrity, cell viability and differentiation. Omega-3 …