The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Small molecule based inhibitors development is a growing field in medicinal chemistry. In
recent years, different heterocyclic derivatives have been designed to counter the infections …

A series of novel 3-aminothiazolquinolones as analogues of quinolone antibacterial agents
were designed and synthesized in an effort to circumvent quinolone resistance. Among …

The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

A novel series of benzimidazole-incorporated sulfonamide analogues were designed and
synthesized with an effort to overcome the increasing antibiotic resistance. Compound 5c …

A series of novel benzimidazole quinolones as potential antimicrobial agents were designed
and synthesized. Most of the prepared compounds exhibited good or even stronger …

Naphthalimide compounds are an important type of nitrogen-containing aromatic
heterocycles with cyclic double imides and the naphthalene framework. This π-deficient …

A series of 5-fluorouracil benzimidazoles as novel type of potential antimicrobial agents
were designed and synthesized for the first time. Bioactive assay manifested that some of …

A series of benzimidazole–quinolone hybrids as new potential antimicrobial agents were
designed and synthesized. Bioactive assays indicated that some of the prepared …

A novel series of benzimidazole derived naphthalimide triazoles and some corresponding
triazoliums have been successfully synthesized and characterized by 1 H NMR, 13 C NMR …