Synthesis of enantioenriched α-heteroatom functionalised aldehydes by chiral organocatalysis and their synthetic applications

PJ Chevis, SG Pyne - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
Asymmetric organocatalysis has proven to be one of the most versatile methods for the
enantioselective α-functionalisation of aldehydes. Initially pioneered by the report of an L …

A simple approach to novel 1, 3-diamino-1, 3-dideoxydihydrosphingosines

M Fábian, K Vargová, T Pončáková, M Martinková… - Tetrahedron …, 2024 - Elsevier
A short and flexible construction of novel dihydrosphingosine-type analogues has been
accomplished. The pivotal step of this approach was a cascade [3, 3]-sigmatropic …

Organocatalyzed Protecting-Group-Free Total Synthesis of (S,S)- and (S,R)-Reboxetine, an Antidepressant Drug

A Sharma, SK Pandey - The Journal of Organic Chemistry, 2022 - ACS Publications
An efficient, simple, and concise organocatalyzed protecting-group-free synthetic approach
to the stereoisomers of the antidepressant drug reboxetine and its implementation toward …

Synthetic Applications of Amino Acid Derived Aldehydes in Asymmetric Hydroxylation Reactions Using Nitrosobenzene

VK Jain, S Dhillon, M Kinger - SynOpen, 2025 - thieme-connect.com
This review highlights the proline-catalyzed asymmetric α-hydroxylation of aldehydes
derived from amino acids. This reaction provides a robust method for introducing a hydroxyl …

Organocatalyzed epoxidation in the total synthesis of (−)-trans-,(+)-trans-and (+)-cis-disparlures

A Sharma, SK Pandey - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
A simple, flexible and efficient organocatalyzed synthetic approach for the synthesis of (−)-
trans-,(+)-trans-and (+)-cis-disparlures has been described. The pivotal reaction sequence …

An efficient enantioselective approach to multifunctionalized γ-butyrolactone: concise synthesis of (+)-nephrosteranic acid

A Gehlawat, R Prakash, SK Pandey - RSC advances, 2020 - pubs.rsc.org
A short, efficient and novel approach for multifunctionalized γ-butyrolactone paraconic acids
and its application to the total synthesis of (+)-nephrosteranic acid from readily available …

A Short and Efficient Enantioselective Synthesis of (+)‐(2S,3S,5S)‐epi‐Muscarine

A Gehlawat, R Prakash, S Kumar Pandey - ChemistrySelect, 2020 - Wiley Online Library
A short, efficient and novel enantioselective general approach for the synthesis of muscarine
alkaloid and its application to the asymmetric synthesis of epi‐muscarine from readily …

Organic Transformations with MeNO 2

D Das, N Patil, BM Bhanage - The Chemical Transformations of …, 2022 - Wiley Online Library
Nitromethane is the simplest organic nitro compound, which is used not only as a solvent but
also as a substantial building block for a variety of important compounds such as …

[PDF][PDF] Enantioselective synthesis of C1-C4 and C5-C14 fragments of cytospolide D.

A Kaur, A Gehlawat, R Prakash… - ARKIVOC: Online Journal …, 2021 - arkat-usa.org
Enantioselective synthesis of C1-C4 and C5-C14 fragments of cytospolide D Page 1 DOI:
https://doi.org/10.24820/ark.5550190.p011.648 Page 1 ©AUTHOR(S) A Platinum Open Access …

Enantioselective Total Synthesis of Sacubitril

A Kaur, A Gehlawat, R Prakash, SK Pandey - ChemistrySelect, 2021 - Wiley Online Library
An efficient enantioselective approach of Sacubitril 1 (a NEP inhibitor) which is used as a
combination drug with Valsartan to treat heart failure, is described. The synthesis features …