Associations of oxidative stress and postoperative outcome in liver surgery with an outlook to future potential therapeutic options

T Senoner, S Schindler, S Stättner… - Oxidative Medicine …, 2019 - Wiley Online Library
Several types of surgical procedures have shown to elicit an inflammatory stress response,
leading to substantial cytokine production and formation of oxygen‐based or nitrogen …

Development of antioxidant COX-2 inhibitors as radioprotective agents for radiation therapy—a hypothesis-driven review

M Laube, T Kniess, J Pietzsch - Antioxidants, 2016 - mdpi.com
Radiation therapy (RT) evolved to be a primary treatment modality for cancer patients.
Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side …

COX-2 expression in hepatocytes improves mitochondrial function after hepatic ischemia-reperfusion injury

M Fuertes-Agudo, M Luque-Tévar, C Cucarella, R Brea… - Antioxidants, 2022 - mdpi.com
Cyclooxygenase 2 (COX-2) is a key enzyme in prostanoid biosynthesis. The constitutive
hepatocyte expression of COX-2 has a protective role in hepatic ischemia-reperfusion (I/R) …

Preconditioning methods in the management of hepatic ischemia reperfusion‐induced injury: Update on molecular and future perspectives

A Suyavaran, C Thirunavukkarasu - Hepatology Research, 2017 - Wiley Online Library
Hepatic IR (ischemia reperfusion) injury is a commonly encountered obstacle in the post‐
operative management of hepatic surgery. Hepatic IR occurs during 'Pringle maneuver'for …

Hyaluronic acid–nimesulide conjugates as anticancer drugs against CD44-overexpressing HT-29 colorectal cancer in vitro and in vivo

YS Jian, CW Chen, CA Lin, HP Yu, HY Lin… - International Journal …, 2017 - Taylor & Francis
Carrier-mediated drug delivery systems are promising therapeutics for targeted delivery and
improved efficacy and safety of potent cytotoxic drugs. Nimesulide is a multifactorial …

n-3 Fatty acids as resolvents of inflammation in the A549 cells

J Gdula-Argasińska, J Czepiel, A Woźniakiewicz… - Pharmacological …, 2015 - Elsevier
Background Fatty acids and their derivatives are one of the most crucial inflammation
mediators. The aim of our study was to evaluate the impact of polyunsaturated fatty acids as …

The propolis and boric acid can be highly suitable, alone/or as a combinatory approach on ovary ischemia-reperfusion injury

F Geyikoglu, K Koc, HS Erol, S Colak, H Ayer… - Archives of gynecology …, 2019 - Springer
Purpose Ovarian ischemia-reperfusion (IR) damage continues to be a serious infertility
problem. The oxidative stress plays central role in the development of IR injuries. Activation …

Effect of tocilizumab on ischemia-reperfusion-induced oxido-inflammatory renal damage and dysfunction in rats

KTO Erdem, Z Bedir, U Kuyrukluyildiz, HG Tas… - Experimental …, 2022 - jstage.jst.go.jp
Ischemia-reperfusion-induced (I/R) renal damage is a pathogenic process that starts with
ischemia, then progresses through oxidative stress and inflammation. Tocilizumab (TCZ), a …

Effect of lutein on oxidants and proinflammatory cytokine-related liver ischemia-reperfusion injury

B GÜNDOĞDU, H Taş, B SÜLEYMAN… - Acta Poloniae …, 2022 - avesis.ebyu.edu.tr
© 2022 Polish Pharmaceutical Society. All rights reserved. Lutein has an anti-inflammatory
impact on tissues, according to recent research. The goal of our research was to see how …

The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway

N Zhang, L Han, Y Xue, Q Deng, Z Wu… - Frontiers in …, 2019 - frontiersin.org
Acute inflammation is an important component of the pathogenesis of hepatic
ischemia/reperfusion injury (HIRI). Magnesium lithospermate B (MLB) has strong …