Poly (2-oxazoline) s based biomaterials: A comprehensive and critical update

T Lorson, MM Luebtow, E Wegener, MS Haider… - Biomaterials, 2018 - Elsevier
Abstract Poly (2-oxazoline) s have been investigated for decades as biomaterials.
Pioneering early work suggested that hydrophilic poly (2-oxazoline) s are comparable to …

The chemistry of poly (2-oxazoline) s

B Verbraeken, BD Monnery, K Lava… - European Polymer …, 2017 - Elsevier
As we celebrate the 50th birthday of the discovery of poly (2-alkyl/aryl-2-oxazoline) s (PAOx)
this year we see a research field that is rapidly expanding after some lesser academic …

Poly (2‐oxazoline) s: A comprehensive overview of polymer structures and their physical properties

M Glassner, M Vergaelen… - Polymer …, 2018 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (PAOx) are of increasing importance for a wide range of
applications, mostly in the biomedical field. This review describes the synthesis of 2 …

Cu-catalyzed azide− alkyne cycloaddition

M Meldal, CW Tornøe - Chemical reviews, 2008 - ACS Publications
The Huisgen 1, 3-dipolar cycloaddition reaction of organic azides and alkynes1, 2 has
gained considerable attention in recent years due to the introduction in 2001 of Cu (1) …

Poly (2‐oxazoline) s: a polymer class with numerous potential applications

R Hoogenboom - Angewandte Chemie International Edition, 2009 - Wiley Online Library
The living cationic ring‐opening polymerization of 2‐oxazolines has been studied in great
detail since its discovery in 1966. The versatility of this living polymerization method allows …

Poly (2‐oxazoline) s as Polymer Therapeutics

R Luxenhofer, Y Han, A Schulz, J Tong… - Macromolecular …, 2012 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (POx) are currently discussed as an upcoming polymer
platform for biomaterials design and especially for polymer therapeutics. POx meet specific …

Synthesis of functional polymers by post‐polymerization modification

MA Gauthier, MI Gibson, HA Klok - … Chemie International Edition, 2009 - Wiley Online Library
Post‐polymerization modification is based on the direct polymerization or copolymerization
of monomers bearing chemoselective handles that are inert towards the polymerization …

'Click'chemistry in polymer and materials science

WH Binder, R Sachsenhofer - Macromolecular Rapid …, 2007 - Wiley Online Library
The modification of polymers after the successful achievement of a polymerization process
represents an important task in macromolecular science. Cycloaddition reactions, among …

1, 3‐Dipolar cycloadditions of azides and alkynes: a universal ligation tool in polymer and materials science

JF Lutz - Angewandte Chemie International Edition, 2007 - Wiley Online Library
In 2001, Sharpless and co‐workers introduced “click” chemistry, a new approach in organic
synthesis that involves a handful of almost perfect chemical reactions. Among these carefully …

Macromolecular engineering through click chemistry and other efficient transformations

BS Sumerlin, AP Vogt - Macromolecules, 2010 - ACS Publications
Precision synthesis of advanced polymeric materials requires efficient, robust, and facile
chemical reactions. Paradoxically, the synthesis of increasingly intricate macromolecular …