Advances in intraoperative flow cytometry

MV D'Amato Figueiredo, GA Alexiou… - International Journal of …, 2022 - mdpi.com
Flow cytometry is the gold-standard laser-based technique to measure and analyze
fluorescence levels of immunostaining and DNA content in individual cells. It provides a …

[HTML][HTML] Detection of cancer cells and tumor margins during colorectal cancer surgery by intraoperative flow cytometry

VK Georvasili, GS Markopoulos, A Batistatou… - International Journal of …, 2022 - Elsevier
Abstract Background Flow Cytometry is an analytical technique for the precise quantification
of cellular phenotype. Intraoperative Flow Cytometry (iFC) utilizes flow cytometry for DNA …

Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas

F De Bacco, F Orzan, G Crisafulli, M Prelli, C Isella… - Cell Reports, 2023 - cell.com
Glioblastoma (GBM) is known as an intractable, highly heterogeneous tumor encompassing
multiple subclones, each supported by a distinct glioblastoma stem cell (GSC). The …

Touch imprint intraoperative flow cytometry as a complementary tool for detailed assessment of resection margins and tumor biology in liver surgery for primary and …

GS Markopoulos, GK Glantzounis, AC Goussia… - Methods and …, 2021 - mdpi.com
Liver resection is the main treatment for primary and metastatic liver tumors in order to
achieve long-term survival with good quality of life. The ultimate goal of surgical oncology is …

Imaging Flow Cytometry: Development, Present Applications, and Future Challenges

S Dimitriadis, L Dova, I Kotsianidis… - Methods and …, 2024 - mdpi.com
Imaging flow cytometry (ImFC) represents a significant technological advancement in the
field of cytometry, effectively merging the high-throughput capabilities of flow analysis with …

Accurate characterization of bladder cancer cells with intraoperative flow cytometry

A Paliouras, GS Markopoulos, S Tsampalas… - Cancers, 2022 - mdpi.com
Simple Summary Bladder cancer is a malignancy that predominantly affects male patients.
Surgical treatment is the first option for clinical management and cancer cell characterization …

Resection margins assessment by intraoperative flow cytometry in pancreatic cancer

GS Markopoulos, A Goussia, CD Bali… - Annals of Surgical …, 2022 - Springer
We read with great interest the landmark article by Shah et al. which efficiently underlines
the importance of resection margins in surgery for pancreatic ductal adenocarcinoma …

An NF-κB-and therapy-related regulatory network in glioma: a potential mechanism of action for natural antiglioma agents

E Vartholomatos, S Mantziou, GA Alexiou, D Lazari… - Biomedicines, 2022 - mdpi.com
High-grade gliomas are among the most aggressive malignancies, with significantly low
median survival. Recent experimental research in the field has highlighted the importance of …

Assessment of gliomas' grade of malignancy and extent of resection using intraoperative flow cytometry

G Vartholomatos, GS Markopoulos, E Vartholomatos… - Cancers, 2023 - mdpi.com
Simple Summary Intraoperative Flow Cytometry (iFC) is a new technique that can help
assess the malignancy grade, diagnose tumor type, and evaluate resection margins during …

Next-generation margin evaluation techniques in breast conserving surgery: A memorandum on intraoperative flow cytometry

G Vartholomatos, GΑ Alexiou, V Tatsi… - European Journal of …, 2023 - ejso.com
An article by Hoffman and Ashkenazi has been recently published in European Journal of
Surgical Oncology, regarding the impact of MarginProbe in the evaluation of resection …