Immunosenescence and human vaccine immune responses
SN Crooke, IG Ovsyannikova, GA Poland… - Immunity & …, 2019 - Springer
The age-related dysregulation and decline of the immune system—collectively termed
“immunosenescence”—has been generally associated with an increased susceptibility to …
“immunosenescence”—has been generally associated with an increased susceptibility to …
A review of zoonotic disease threats to pet owners: A compendium of measures to prevent zoonotic diseases associated with non-traditional pets such as rodents and …
K Varela, JA Brown, B Lipton, J Dunn… - Vector-Borne and …, 2022 - liebertpub.com
Background......................................................................... 305 I. Rodents and other small
mammals.......................................... 309 II. Reptiles (turtles, snakes, and …
mammals.......................................... 309 II. Reptiles (turtles, snakes, and …
The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets
SARS-CoV-2 entry requires sequential cleavage of the spike glycoprotein at the S1/S2 and
the S2ʹ cleavage sites to mediate membrane fusion. SARS-CoV-2 has a polybasic insertion …
the S2ʹ cleavage sites to mediate membrane fusion. SARS-CoV-2 has a polybasic insertion …
Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway
SARS-CoV-2 has a broad mammalian species tropism infecting humans, cats, dogs, and
farmed mink. Since the start of the 2019 pandemic, several reverse zoonotic outbreaks of …
farmed mink. Since the start of the 2019 pandemic, several reverse zoonotic outbreaks of …
The furin cleavage site of SARS-CoV-2 spike protein is a key determinant for transmission due to enhanced replication in airway cells
TP Peacock, DH Goldhill, J Zhou, L Baillon, R Frise… - BioRxiv, 2020 - biorxiv.org
SARS-CoV-2 enters cells via its spike glycoprotein which must be cleaved sequentially at
the S1/S2, then the S2'cleavage sites (CS) to mediate membrane fusion. SARS-CoV-2 has a …
the S1/S2, then the S2'cleavage sites (CS) to mediate membrane fusion. SARS-CoV-2 has a …
Hemagglutinin stability and its impact on influenza A virus infectivity, pathogenicity, and transmissibility in avians, mice, swine, seals, ferrets, and humans
CJ Russell - Viruses, 2021 - mdpi.com
Genetically diverse influenza A viruses (IAVs) circulate in wild aquatic birds. From this
reservoir, IAVs sporadically cause outbreaks, epidemics, and pandemics in wild and …
reservoir, IAVs sporadically cause outbreaks, epidemics, and pandemics in wild and …
Recurrent mutations in SARS-CoV-2 genomes isolated from mink point to rapid host-adaptation
Severe acute respiratory coronavirus 2 (SARS-CoV-2), the agent of the ongoing COVID-19
pandemic, jumped into humans from an unknown animal reservoir in late 2019. In line with …
pandemic, jumped into humans from an unknown animal reservoir in late 2019. In line with …
Animal models for influenza research: strengths and weaknesses
Influenza remains one of the most significant public health threats due to its ability to cause
high morbidity and mortality worldwide. Although understanding of influenza viruses has …
high morbidity and mortality worldwide. Although understanding of influenza viruses has …
Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity
AJG Jansen, T Spaan, HZ Low, D Di Iorio… - Blood …, 2020 - ashpublications.org
Thrombocytopenia is a common complication of influenza virus infection, and its severity
predicts the clinical outcome of critically ill patients. The underlying cause (s) remain …
predicts the clinical outcome of critically ill patients. The underlying cause (s) remain …
Block the Spread: Barriers to Transmission of Influenza Viruses
V Le Sage, AC Lowen… - Annual Review of …, 2023 - annualreviews.org
Respiratory viruses, such as influenza viruses, cause significant morbidity and mortality
worldwide through seasonal epidemics and sporadic pandemics. Influenza viruses transmit …
worldwide through seasonal epidemics and sporadic pandemics. Influenza viruses transmit …