Host-microbe interactions at the blood-brain barrier through the lens of induced pluripotent stem cell-derived brain-like endothelial cells
Microbe-induced meningoencephalitis/meningitis is a life-threatening infection of the central
nervous system (CNS) that occurs when pathogens are able to cross the blood-brain barrier …
nervous system (CNS) that occurs when pathogens are able to cross the blood-brain barrier …
Coxsackievirus B3 infects and disrupts human induced-pluripotent stem cell derived brain-like endothelial cells
J Mamana, GM Humber, ER Espinal, S Seo… - Frontiers in Cellular …, 2023 - frontiersin.org
Coxsackievirus B3 (CVB3) is a significant human pathogen that is commonly found
worldwide. CVB3 among other enteroviruses, are the leading causes of aseptic meningo …
worldwide. CVB3 among other enteroviruses, are the leading causes of aseptic meningo …
Blood-tumor barrier in focus-investigation of glioblastoma-induced effects on the blood-brain barrier
S Mathew-Schmitt, M Peindl, P Neundorf… - Journal of neuro …, 2024 - Springer
Purpose Glioblastoma (GBM) is the most prevalent, malignant, primary brain tumor in adults,
characterized by limited treatment options, frequent relapse, and short survival after …
characterized by limited treatment options, frequent relapse, and short survival after …
Synthesis and Characterization of quercetin–iron complex nanoparticles for overcoming drug resistance
L Prestianni, ER Espinal, SF Hathcock, N Vollmuth… - Pharmaceutics, 2023 - mdpi.com
Quercetin, one of the major natural flavonoids, has demonstrated great pharmacological
potential as an antioxidant and in overcoming drug resistance. However, its low aqueous …
potential as an antioxidant and in overcoming drug resistance. However, its low aqueous …
Human-Induced Pluripotent Stem Cell-Based Model of the Blood-Brain at 10 Years: A Retrospective on Past and Current Disease Models
AJ Al-Ahmad - Human iPSC-derived Disease Models for Drug …, 2023 - Springer
The initial discovery and derivation of induced pluripotent stem cells (iPSCs) by Yamanaka
and colleagues in 2006 revolutionized the field of personalized medicine, as it opened the …
and colleagues in 2006 revolutionized the field of personalized medicine, as it opened the …
Transcriptomic analysis of coxsackievirus B3 infection in induced pluripotent stem cell-derived brain-like endothelial cells
SF Hathcock, J Mamana, TE Keyzer… - Journal of …, 2024 - journals.asm.org
Viral aseptic meningitis is a neuroinflammatory condition that occurs when viruses gain
access to the central nervous system (CNS) and induce inflammation. The blood–brain …
access to the central nervous system (CNS) and induce inflammation. The blood–brain …
Group B Streptococcus transcriptome when interacting with brain endothelial cells
N Vollmuth, BE Bridgers, ML Armstrong… - Journal of …, 2024 - Am Soc Microbiol
Bacterial meningitis is a life-threatening infection of the central nervous system (CNS) that
occurs when bacteria are able to cross the blood–brain barrier (BBB) or the meningeal …
occurs when bacteria are able to cross the blood–brain barrier (BBB) or the meningeal …
[HTML][HTML] Common Chemical Plasticizer Di (2-Ethhylhexyl) Phthalate Exposure Exacerbates Coxsackievirus B3 Infection
R Kordbacheh, M Ashley, WD Cutts, TE Keyzer… - Viruses, 2024 - mdpi.com
Di (2-ethhylhexyl) phthalate (DEHP) is a common plastic rubberizer. DEHP leaches from
plastic matrices and is under increasing scrutiny as numerous studies have linked it to …
plastic matrices and is under increasing scrutiny as numerous studies have linked it to …
iPS 細胞由来脳血管内皮細胞とBBB モデル
山口朋子， 川端健二 - Drug Delivery System, 2023 - jstage.jst.go.jp
抄録 血液-脳関門 (blood brain barrier: BBB) は, 血中に侵入した病原体や毒性物質が脳に移行
するのを防ぐために備わったバリアーである. しかしながら, BBB の存在ゆえに薬物は脳に到達し …
するのを防ぐために備わったバリアーである. しかしながら, BBB の存在ゆえに薬物は脳に到達し …