Epstein–Barr virus in the pathogenesis of NPC

N Raab-Traub - Seminars in cancer biology, 2002 - Elsevier
Epstein–Barr virus (EBV) is consistently detected in nasopharyngeal carcinoma (NPC) from
regions of high and low incidence. EBV DNA within the tumor is homogeneous with regard …

Epstein-Barr virus latent membrane protein 1: structure and functions

HP Li, YS Chang - Journal of biomedical science, 2003 - karger.com
Abstract The Epstein-Barr virus latent membrane protein (LMP) 1 is a versatile protein that
has profound effects on target cells through its effect on constitutive cellular proteins, eg …

Human tumor virus utilizes exosomes for intercellular communication

DG Meckes Jr, KHY Shair… - Proceedings of the …, 2010 - National Acad Sciences
The Epstein–Barr virus (EBV) latent membrane protein 1 (LMP1) is expressed in multiple
human malignancies and has potent effects on cell growth. It has been detected in …

Clonal proliferations of cells infected with Epstein–Barr virus in preinvasive lesions related to nasopharyngeal carcinoma

R Pathmanathan, U Prasad, R Sadler… - … England Journal of …, 1995 - Mass Medical Soc
Background The Epstein–Barr virus (EBV) is consistently detected in patients with
nasopharyngeal carcinoma. To determine whether EBV infection is an early, initiating event …

Epstein–Barr virus microRNAs are evolutionarily conserved and differentially expressed

X Cai, A Schäfer, S Lu, JP Bilello, RC Desrosiers… - PLoS …, 2006 - journals.plos.org
The pathogenic lymphocryptovirus Epstein–Barr virus (EBV) is shown to express at least 17
distinct microRNAs (miRNAs) in latently infected cells. These are arranged in two clusters …

Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts

L Brooks, QY Yao, AB Rickinson, LS Young - Journal of virology, 1992 - Am Soc Microbiol
Epstein-Barr virus (EBV) genome-positive nasopharyngeal carcinomas (NPCs) regularly
express the virus-coded nuclear antigen EBNA1, but not other EBNAs, and a subset of …

A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses

A Grundhoff, CS Sullivan, D Ganem - Rna, 2006 - rnajournal.cshlp.org
We have developed an approach to identify microRNAs (miRNAs) that is based on
bioinformatics and array-based technologies, without the use of cDNA cloning. The …

Undifferentiated, nonkeratinizing, and squamous cell carcinoma of the nasopharynx. Variants of Epstein-Barr virus-infected neoplasia.

R Pathmanathan, U Prasad, G Chandrika… - The American journal …, 1995 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) samples of distinct histological types, including
squamous cell carcinoma (WHO type 1), nonkeratinizing carcinoma (WHO type 2), and …

Epstein-Barr virus and Hodgkin's disease: transcriptional analysis of virus latency in the malignant cells.

EM Deacon, G Pallesen, G Niedobitek… - The Journal of …, 1993 - rupress.org
Epstein-Barr virus (EBV) is associated with a number of different human tumors and appears
to play different pathogenetic roles in each case. Thus, immunoblastic B cell lymphomas of …

Epstein-Barr virus latency in blood mononuclear cells: analysis of viral gene transcription during primary infection and in the carrier state

RJ Tierney, N Steven, LS Young… - Journal of virology, 1994 - Am Soc Microbiol
Epstein-Barr virus (EBV) can display different forms of latent infection in B-cell lines in vitro;
however, the types of infection normally established by the virus in vivo remain largely …