Ageing is accompanied by 2–4-fold increases in plasma/serum levels of inflammatory
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …

Dementia is a complex human disease. The incidence of dementia among the elderly
population is rising rapidly worldwide. In the United States, Alzheimer's disease (AD) is the …

BACKGROUND: Studies suggest that inflammation is involved in the neurodegenerative
cascade leading to Alzheimer's disease (AD) pathology and symptoms. This study sought to …

Chronic inflammation is associated with a broad spectrum of neurodegenerative diseases of
aging. Included are such disorders as Alzheimer's disease (AD), Parkinson's disease (PD) …

Neuroinflammation is a central feature of Alzheimer disease (AD). It involves an innate
immune reaction of sufficient intensity that self attack on neurons occurs. This phenomenon …

Gallic acid (3, 4, 5-trihydroxybenzoic acid) is a phenolic acid widely distributed in many
different families of higher plants, both in free state, and as a part of more complex …

Neuroinflammation is a characteristic of pathologically affected tissue in several
neurodegenerative disorders. These changes are particularly observed in affected brain …

Background Inflammation is believed to play an important role in the pathology of
Alzheimer's disease (AD) and cytokine production is a key pathologic event in the …

A direct relationship exists between aging and increasing incidences of chronic diseases. In
fact, with most age-associated diseases individuals manifest an underlying chronic …

The decline in mental fitness associated with Alzheimer disease is accompanied by physical
changes in the brain, including the development of characteristic plaques and neurofibrillary …