Hematopoietic cell transplantation is used to treat malignancies, hematologic and immune
deficiency states, marrow failure syndromes, and autoimmune diseases. Graft-versus-host …

Graft-versus-host disease (GVHD) is defined by the aggregation of clinical and pathological
manifestations in a recipient of allogeneic stem cells or bone marrow transplantation in …

Objective. To assess the efficacy of rituximab (RTX) in SSc. Methods. Fourteen patients with
SSc were evaluated. Eight patients were randomized to receive two cycles of RTX at …

The use of fetal bovine serum (FBS) for the culture and expansion of mesenchymal stromal
cells (MSCs) limits their possible clinical applications. Although some recent studies …

Hematopoietic stem cell transplantation (HSCT) is widely used as a potentially curative
treatment for patients with various hematological malignancies, bone marrow failure …

Manifestations of chronic graft-versus-host disease (cGVHD) can resemble those seen in
immunodeficiency states and autoimmune disorders. Reports by us and others suggest an …

Several grading systems have been developed in the bone marrow transplantation setting in
attempts to predict survival in patients with chronic graft-versus-host disease (cGVHD). In …

Allogeneic hematopoietic cell transplantation (allo-HCT) is considered to be a curative
treatment of many hematologic malignancies as well as for a wide range of hematologic and …

Introduction The field of allogeneic hematopoietic cell transplantation (allo‐HCT) began in
the 1950s, and despite a seven decade history of remarkable clinical advances, graft‐versus …

Protein kinases are fundamental components of diverse signaling pathways, including
immune cells. Their essential functions have made them effective therapeutic targets …