Structural determination, total synthesis, and biological activity of iezoside, a highly potent Ca2+-ATPase inhibitor from the marine cyanobacterium Leptochromothrix …

N Kurisawa, A Iwasaki, K Teranuma… - Journal of the …, 2022 - ACS Publications
Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) is a membrane protein on the
endoplasmic reticulum (ER) that transports Ca2+ from the cytosol into the ER. As its function …

Recent Development in the Synthesis of Thiazoles

DX Duc, NT Chung - Current Organic Synthesis, 2022 - ingentaconnect.com
Background: Thiazole-containing compounds are widely found in natural products as well
as synthetic sources. Many thiazole-based compounds possess a broad spectrum of …

Ynamide-mediated thioamide and primary thioamide syntheses

C Wang, C Han, J Yang, Z Zhang… - The Journal of Organic …, 2022 - ACS Publications
Environmentally friendly ynamide-mediated thioamidation of monothiocarboxylic acids with
amines or ammonium hydroxide for the syntheses of thioamides and primary thioamides is …

2-Amino-4-(aminomethyl) thiazole-based derivatives as potential antitumor agents: design, synthesis, cytotoxicity and apoptosis inducing activities

M Liao, D Huang, YX Cheng - Mendeleev Communications, 2023 - Elsevier
Abstract Novel 2-amino-4-(aminomethyl) thiazole derivatives were designed and
synthesized by a facile method including the Hantzsch construction of thiazole core followed …