Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): a review of clinical and MRI features, diagnosis, and management

E Sechi, L Cacciaguerra, JJ Chen, S Mariotto… - Frontiers in …, 2022 - frontiersin.org
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is the
most recently defined inflammatory demyelinating disease of the central nervous system …

Myelin oligodendrocyte glycoprotein antibodies in neurological disease

M Reindl, P Waters - Nature Reviews Neurology, 2019 - nature.com
Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected
by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …

Role of B cells in multiple sclerosis and related disorders

G Comi, A Bar‐Or, H Lassmann, A Uccelli… - Annals of …, 2021 - Wiley Online Library
The success of clinical trials of selective B‐cell depletion in patients with relapsing multiple
sclerosis (MS) and primary progressive MS has led to a conceptual shift in the …

Reassessing B cell contributions in multiple sclerosis

R Li, KR Patterson, A Bar-Or - Nature immunology, 2018 - nature.com
There is growing recognition that B cell contributions to normal immune responses extend
well beyond their potential to become antibody-producing cells, including roles at the innate …

B cells in autoimmune and neurodegenerative central nervous system diseases

JJ Sabatino Jr, AK Pröbstel, SS Zamvil - Nature Reviews Neuroscience, 2019 - nature.com
B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and …

J Kuhle, C Barro, U Andreasson, T Derfuss… - Clinical Chemistry and …, 2016 - degruyter.com
Background: Neuronal damage is the morphological substrate of persisting neurological
disability. Neurofilaments (Nf) are specific cytoskeletal proteins of neurons and their …

Molecular biomarkers in multiple sclerosis

T Ziemssen, K Akgün, W Brück - Journal of neuroinflammation, 2019 - Springer
Multiple sclerosis (MS) is an inflammatory-neurodegenerative disease of the central nervous
system presenting with significant inter-and intraindividual heterogeneity. However, the …

Multiple sclerosis and myelin basic protein: Insights into protein disorder and disease

V Martinsen, P Kursula - Amino Acids, 2022 - Springer
Myelin basic protein (MBP) is an abundant protein in central nervous system (CNS) myelin.
MBP has long been studied as a factor in the pathogenesis of the autoimmune …

Neurological update: MOG antibody disease

R Wynford-Thomas, A Jacob, V Tomassini - Journal of neurology, 2019 - Springer
Myelin oligodendrocyte glycoprotein (MOG) antibody disease (MOG-AD) is now recognised
as a nosological entity with specific clinical and paraclinical features to aid early diagnosis …

Myelin oligodendrocyte glycoprotein antibody-associated disease: current insights into the disease pathophysiology, diagnosis and management

W Ambrosius, S Michalak, W Kozubski… - International journal of …, 2020 - mdpi.com
Myelin oligodendrocyte glycoprotein (MOG)-associated disease (MOGAD) is a rare,
antibody-mediated inflammatory demyelinating disorder of the central nervous system …