M Reindl, P Waters - Nature Reviews Neurology, 2019 - nature.com
Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …
G Comi, A Bar‐Or, H Lassmann, A Uccelli… - Annals of …, 2021 - Wiley Online Library
The success of clinical trials of selective B‐cell depletion in patients with relapsing multiple sclerosis (MS) and primary progressive MS has led to a conceptual shift in the …
R Li, KR Patterson, A Bar-Or - Nature immunology, 2018 - nature.com
There is growing recognition that B cell contributions to normal immune responses extend well beyond their potential to become antibody-producing cells, including roles at the innate …
B cells are essential components of the adaptive immune system and have important roles in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …
Background: Neuronal damage is the morphological substrate of persisting neurological disability. Neurofilaments (Nf) are specific cytoskeletal proteins of neurons and their …
T Ziemssen, K Akgün, W Brück - Journal of neuroinflammation, 2019 - Springer
Multiple sclerosis (MS) is an inflammatory-neurodegenerative disease of the central nervous system presenting with significant inter-and intraindividual heterogeneity. However, the …
V Martinsen, P Kursula - Amino Acids, 2022 - Springer
Myelin basic protein (MBP) is an abundant protein in central nervous system (CNS) myelin. MBP has long been studied as a factor in the pathogenesis of the autoimmune …
R Wynford-Thomas, A Jacob, V Tomassini - Journal of neurology, 2019 - Springer
Myelin oligodendrocyte glycoprotein (MOG) antibody disease (MOG-AD) is now recognised as a nosological entity with specific clinical and paraclinical features to aid early diagnosis …
W Ambrosius, S Michalak, W Kozubski… - International journal of …, 2020 - mdpi.com
Myelin oligodendrocyte glycoprotein (MOG)-associated disease (MOGAD) is a rare, antibody-mediated inflammatory demyelinating disorder of the central nervous system …