The possible role of brain-derived neurotrophic factor in epilepsy

R AlRuwaili, HM Al-Kuraishy, AI Al-Gareeb… - Neurochemical …, 2024 - Springer
Epilepsy is a neurological disease characterized by repeated seizures. Despite of that the
brain-derived neurotrophic factor (BDNF) is implicated in the pathogenesis of …

The role of brain-derived neurotrophic factor in epileptogenesis: an update

X Wang, Z Hu, K Zhong - Frontiers in Pharmacology, 2021 - frontiersin.org
Epilepsy, which is characterized by spontaneous recurrent seizures, is one of the most
common and serious chronic neurological diseases in the world. 30% patients failed to …

Genotype-expression interactions for BDNF across human brain regions

P Devlin, X Cao, AG Stanfill - BMC genomics, 2021 - Springer
Background Genetic variations in brain-derived neurotrophic factor (BDNF) are associated
with various psychiatric disorders including depression, obsessive-compulsive disorder …

[Retracted] Potential Pleiotropic Genes and Shared Biological Pathways in Epilepsy and Depression Based on GWAS Summary Statistics

H Lin, WH Lin, F Lin, CY Liu, CH Che… - Computational …, 2022 - Wiley Online Library
Current epidemiological and experimental studies have indicated the overlapping genetic
foundation of epilepsy and depression. However, the detailed pleiotropic genetic etiology …

Epigenome-wide association study of seizures in childhood and adolescence

D Caramaschi, C Hatcher, RH Mulder, JF Felix… - Clinical …, 2020 - Springer
The occurrence of seizures in childhood is often associated with neurodevelopmental
impairments and school underachievement. Common genetic variants associated with …

[HTML][HTML] 神经系统疾病与认知动力学(I): 癫痫发作的动力学与控制

韩芳, 樊登贵, 张丽媛, 王青云 - 力学进展, 2022 - pubs.cstam.org.cn
研究表明癫痫发作过程与神经系统本身的非线性动力学行为密切相关. 因此,
开展癫痫发作的非线性网络动力学建模与调控问题的研究, 有助于理解癫痫临床表征的动力学 …

Significant association of BDNF rs6265 G>A polymorphism with susceptibility to epilepsy: a meta-analysis

YL Xu, XX Li, SJ Zhuang, SF Guo… - Neuropsychiatric …, 2018 - Taylor & Francis
Introduction Previously published articles have suggested that BDNF rs6265 G> A
polymorphism is a potential risk factor for epilepsy. However, the results were not consistent …

Combined melatonin and adrenocorticotropic hormone treatment attenuates N-methyl-d-aspartate-induced infantile spasms in a rat model by regulating activation of …

L Wan, G Yang, Y Sun, Z Li, S Zhang, X Shi, J Wang - Neuroscience Letters, 2021 - Elsevier
Infantile spasms (IS) is a serious epileptic syndrome that frequently occurs in infancy.
Adrenocorticotropic hormone (ACTH) is generally the first-line treatment for IS; however …

Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice

N Sarahian, MT Mohammadi, S Darabi, N Faghihi - Brain Research, 2021 - Elsevier
Epileptic seizures are the most common neurological diseases that change the function of
neurovascular unit at molecular levels accompanied by activation of a wide variety of …

[HTML][HTML] A new comorbidity model and the common pathological mechanisms of migraine and epilepsy

S Fan, Z Xiao, F Zhu, X He, Z Lu - American Journal of …, 2017 - ncbi.nlm.nih.gov
A bi-directional relationship between epilepsy and migraine has been widely reported in
epidemiological and clinical studies, but the mechanisms of interaction between these …