To Erase or not to erase: non-canonical catalytic functions and non-catalytic functions of members of histone lysine demethylase families
E Di Nisio, V Manzini, V Licursi, R Negri - International Journal of …, 2024 - mdpi.com
Histone lysine demethylases (KDMs) play an essential role in biological processes such as
transcription regulation, RNA maturation, transposable element control, and genome …
transcription regulation, RNA maturation, transposable element control, and genome …
Versatile JMJD proteins: juggling histones and much more
S Oh, R Janknecht - Trends in Biochemical Sciences, 2024 - cell.com
Jumonji C domain-containing (JMJD) proteins are found in bacteria, fungi, animals, and
plants. They belong to the 2-oxoglutarate-dependent oxygenase superfamily and are …
plants. They belong to the 2-oxoglutarate-dependent oxygenase superfamily and are …
A constitutional isomer selective chemical proteomic strategy for system-wide profiling of protein lysine 5-hydroxylation
Lysine 5-hydroxylation (5-Hyl) has been well recognized as an essential protein post-
translational modification regulating cellular structural stability, RNA alternative splicing and …
translational modification regulating cellular structural stability, RNA alternative splicing and …
Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia
T Ji, Y Yang, J Yu, H Yin, X Chu, P Yang, L Xu… - Journal of Experimental …, 2024 - Springer
Background Despite the use of targeted therapeutic approaches, T-cell acute lymphoblastic
leukemia (T-ALL) is still associated with a high incidence of complications and a poor …
leukemia (T-ALL) is still associated with a high incidence of complications and a poor …