Vitamin D, autoimmune disease and rheumatoid arthritis

SR Harrison, D Li, LE Jeffery, K Raza… - Calcified tissue …, 2020 - Springer
Vitamin D has been reported to influence physiological systems that extend far beyond its
established functions in calcium and bone homeostasis. Prominent amongst these are the …

Association of vitamin D metabolism gene polymorphisms with autoimmunity: evidence in population genetic studies

AI Ruiz-Ballesteros, MR Meza-Meza… - International journal of …, 2020 - mdpi.com
A high prevalence of vitamin D (calcidiol) serum deficiency has been described in several
autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis (AR), and …

Vitamin D and genetic susceptibility to multiple sclerosis

C Scazzone, L Agnello, G Bivona, B Lo Sasso… - Biochemical …, 2021 - Springer
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system
(CNS), resulting from the interaction among genetic, epigenetic, and environmental factors …

[HTML][HTML] A review of the critical role of vitamin D axis on the immune system

G Daryabor, N Gholijani, FR Kahmini - Experimental and Molecular …, 2023 - Elsevier
In recent years, the physiological and molecular functions of vitamin D (Vit-D) have been
deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal …

Association between vitamin D receptor (VDR) polymorphisms and the risk of multiple sclerosis (MS): an updated meta-analysis

D Imani, B Razi, M Motallebnezhad, R Rezaei - BMC neurology, 2019 - Springer
Background The association between the Vitamin D Receptor (VDR) gene polymorphism
and the risk of Multiple sclerosis (MS) has been evaluated in several researches. However …

Association between polymorphisms in the vitamin D receptor and susceptibility to multiple sclerosis

BC Díez, C Pérez-Ramírez… - Pharmacogenetics …, 2021 - journals.lww.com
Objectives Multiple sclerosis (MS) is a neurodegenerative chronic inflammatory. Mutations in
the vitamin D receptor (VDR) gene can substantially affect serum vitamin D levels or alter its …

Vitamin D and Disease severity in multiple sclerosis—baseline data from the randomized controlled trial (EVIDIMS)

P Bäcker-Koduah, J Bellmann-Strobl, M Scheel… - Frontiers in …, 2020 - frontiersin.org
Objective: To investigate the associations between hypovitaminosis D and disease activity in
a cohort of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome …

Exonic variants of genes related to the vitamin D signaling pathway in the families of familial multiple sclerosis using whole‐exome next generation sequencing

V Pytel, JA Matías‐Guiu, L Torre‐Fuentes… - Brain and …, 2019 - Wiley Online Library
Abstract Introduction Vitamin D (VD) deficiency has been associated with multiple sclerosis
(MS) and other autoimmune diseases (AIDs). However, the effect of the genetics of VD on …

Vitamin D and demyelinating diseases: neuromyelitis optica (NMO) and multiple sclerosis (MS)

C Rodney, S Rodney, RM Millis - Autoimmune diseases, 2020 - Wiley Online Library
Vitamin D deficiency is prevalent in all ages regardless of climate or geographical location
and evidence is emerging that the incidence of autoimmune diseases is increasing …

Vitamin D receptor and its influence on multiple sclerosis risk and severity: from gene polymorphisms to protein expression

C Pistono, C Osera, MC Monti, C Boiocchi, G Mallucci… - Immuno, 2022 - mdpi.com
Multiple sclerosis (MS) is a multifactorial neurodegenerative disease. Low levels of vitamin
D are a risk factor for MS and alterations in the vitamin D receptor (VDR) might be a risk …