Droplet microfluidics for microbiology: techniques, applications and challenges
Droplet microfluidics has rapidly emerged as one of the key technologies opening up new
experimental possibilities in microbiology. The ability to generate, manipulate and monitor …
experimental possibilities in microbiology. The ability to generate, manipulate and monitor …
Droplet microfluidics for high-throughput analysis of antibiotic susceptibility in bacterial cells and populations
W Postek, P Garstecki - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Antibiotic-resistant bacteria are an increasing concern both in everyday life and
specialized environments such as healthcare. As the rate of antibiotic-resistant infections …
specialized environments such as healthcare. As the rate of antibiotic-resistant infections …
Single-cell pathogen diagnostics for combating antibiotic resistance
Bacterial infections and antimicrobial resistance are a major cause for morbidity and
mortality worldwide. Antimicrobial resistance often arises from antimicrobial misuse, where …
mortality worldwide. Antimicrobial resistance often arises from antimicrobial misuse, where …
Microfluidics for antibiotic susceptibility testing
W Postek, N Pacocha, P Garstecki - Lab on a Chip, 2022 - pubs.rsc.org
The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …
Recent progress in microfluidics-based biosensing
Y Song, B Lin, T Tian, X Xu, W Wang, Q Ruan… - Analytical …, 2018 - ACS Publications
Biosensors are analytical devices or systems used to detect a specific target by converting
and amplifying a biomolecular recognition event to a dateable semiquantitative or …
and amplifying a biomolecular recognition event to a dateable semiquantitative or …
Pathogenic bacteria detection using RNA-based loop-mediated isothermal-amplification-assisted nucleic acid amplification via droplet microfluidics
Nucleic acid amplifications, such as polymerase chain reaction (PCR), are very beneficial for
diagnostic applications, especially in the context of bacterial or viral outbreaks due to their …
diagnostic applications, especially in the context of bacterial or viral outbreaks due to their …
Combating antimicrobial resistance via single-cell diagnostic technologies powered by droplet microfluidics
Conspectus Antimicrobial resistance is a global threat that if left unchecked could lead to 10
million annual mortalities by 2050. One factor contributing to the rise of multi-drug-resistant …
million annual mortalities by 2050. One factor contributing to the rise of multi-drug-resistant …
Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population
Since antibiotic resistance is a major threat to global health, recent observations that the
traditional test of minimum inhibitory concentration (MIC) is not informative enough to guide …
traditional test of minimum inhibitory concentration (MIC) is not informative enough to guide …
Droplet microfluidics for high‐sensitivity and high‐throughput detection and screening of disease biomarkers
Biomarkers are nucleic acids, proteins, single cells, or small molecules in human tissues or
biological fluids whose reliable detection can be used to confirm or predict disease and …
biological fluids whose reliable detection can be used to confirm or predict disease and …
Simple and precise counting of viable bacteria by resazurin-amplified picoarray detection
Simple, fast, and precise counting of viable bacteria is fundamental to a variety of
microbiological applications such as food quality monitoring and clinical diagnosis. To this …
microbiological applications such as food quality monitoring and clinical diagnosis. To this …